Bio-Techne and Wyss Center Team Up to Advance 3D Spatial Biology

Pushing the Frontiers of Multiomics Research

Bio-Techne has announced a strategic collaboration with the Wyss Center for Bio and Neuroengineering in Geneva to advance the next generation of spatial biology. The partnership focuses on developing an automated three-dimensional (3D) multiomics workflow capable of simultaneously detecting RNA and protein within intact tissue samples. This initiative represents an important step toward understanding biological systems in their full spatial complexity, enabling researchers to explore cellular interactions and tissue architecture beyond traditional two-dimensional analysis.

Bringing 3D Biology into Everyday Research

While existing spatial biology technologies have delivered powerful insights at the two-dimensional level, they remain limited when applied to thick or complex tissue structures. Manual methods for 3D analysis are often time-consuming, technically demanding, and difficult to scale. Through this collaboration, Bio-Techne and the Wyss Center aim to automate RNA and protein profiling in three-dimensional specimens, reducing technical barriers and making advanced spatial biology approaches more accessible to a wider research community.

Transforming Preclinical Studies and Biological Modeling

High-resolution 3D multiomic analysis has the potential to significantly accelerate preclinical research, including organoid development, drug discovery, and predictive disease modeling. By capturing molecular information within intact tissues, researchers can generate more physiologically relevant models that better reflect human biology. This improved fidelity may reduce reliance on animal models while supporting faster and more ethical therapeutic development.

Combining Expertise to Expand Scientific Capability

The collaboration brings together complementary strengths. Bio-Techne contributes its established expertise in RNA and protein detection technologies, while the Wyss Center offers leadership in translational research, bioengineering, and advanced neuroscience. Together, the partners are building scalable workflows designed to integrate seamlessly into modern research environments, supporting the growing demand for multidimensional biological data.

Key Highlights

1.Joint development of automated 3D multiomic workflows

2.Simultaneous RNA and protein detection in intact tissue samples

3.Deeper insight into cellular architecture and spatial relationships

4.Enables advanced modeling for drug discovery and translational research

5. Designed to lower technical barriers in spatial biology adoption

Applications

1.Organoid research and complex tissue modeling

2.Drug discovery and therapeutic optimization

3.Diagnostic innovation and translational science

4.AI-driven predictive biological modeling

5.Three-dimensional systems biology analysis

Expanding the Reach of Spatial Biology

This partnership aligns with Bio-Techne’s broader mission to democratize spatial biology by delivering tools that reflect the increasing complexity of modern biomedical research. By automating 3D multiomic analysis, scientists can investigate biological systems in their native context with greater precision, efficiency, and scalability—accelerating discovery and supporting more informed decision-making across research and development.