Illumina Launches StrataMap Spatial Research Solution

New end-to-end spatial transcriptomics platform delivers true single-cell resolution for advanced biological research

Illumina has introduced the StrataMap™ Spatial Solution, an end-to-end sequencing-based research platform designed to transform spatial transcriptomics. The new solution enables researchers to study gene expression at true single-cell resolution across large tissue sections, providing deeper insights into tissue architecture, disease progression and cellular interactions. It is expected to accelerate discoveries in oncology, neuroscience and developmental biology.

Advancing Spatial Biology Research

StrataMap Spatial combines whole-transcriptome sequencing with high-resolution spatial analysis, allowing scientists to examine where genes are expressed within intact tissues. Unlike targeted probe-based approaches, the platform provides unbiased transcriptome profiling, helping researchers identify rare cell populations, investigate tissue organization and better understand complex biological systems. This comprehensive workflow simplifies spatial biology studies while delivering richer genomic insights.

Improving Discovery with High-Resolution Analysis

The solution features a large and flexible tissue capture area together with true single-cell spatial resolution, enabling researchers to analyze more tissue in a single experiment. Illumina states that the sequencing-based approach can detect approximately twice as many unique genes per sample compared with probe-based technologies, supporting more comprehensive studies in precision medicine and translational research.

Accelerating Precision Medicine Innovation

StrataMap Spatial is designed to support research into cancer biology, neuroscience, immunology and developmental biology by revealing how cells interact within their natural tissue environments. By integrating advanced sequencing with dedicated bioinformatics tools, the platform enables researchers to generate high-quality spatial data that can help identify new biomarkers, understand disease mechanisms and accelerate therapeutic development.

Key Features

1. End-to-end spatial transcriptomics solution
2. True single-cell spatial resolution
3. Whole-transcriptome sequencing
4. Large tissue capture area
5. Unbiased gene expression profiling

Applications

1. Oncology research
2. Neuroscience research
3. Developmental biology
4. Precision medicine
5. Biomarker discovery

Expanding the Future of Spatial Genomics

Illumina's StrataMap Spatial Solution marks an important advancement in spatial biology by combining comprehensive transcriptome profiling with high-resolution tissue analysis. The platform provides researchers with powerful tools to better understand cellular function and tissue organization, supporting the next generation of biomedical discoveries and precision medicine research.