1612700
Simvastatin
United States Pharmacopeia (USP) Reference Standard
Manufacturer: Sigma Aldrich
CAS Number: 79902-63-9
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 200 MG | 1612700-200-MG | In Stock | ₹ 40,756.13 |
1612700 - 200 MG
In Stock
Quantity
1
Base Price: ₹ 40,756.13
GST (18%): ₹ 7,336.103
Total Price: ₹ 48,092.233
grade
pharmaceutical primary standard
API family
simvastatin
manufacturer/tradename
USP
technique(s)
HPLC: suitablegas chromatography (GC): suitable
mp
127-132 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
InChI
1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI key
RYMZZMVNJRMUDD-HGQWONQESA-N
Other Options
Related Products
Description
- General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
- Application: Simvastatin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
- Biochem/physiol Actions: Simvastatin is a specific inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. It is used in the treatment of hypercholesterolemia, as it reduces levels of low-density lipoproteins and triglycerides, and raises high-density lipoprotein levels. Simvastatin is a lactone that is readily hydrolyzed in vivo to the corresponding β-hydroxyacid, and can be activated prior to use with NaOH in EtOH treatment. It is a synthetic analog of lovastatin (Cat. No. M2147).
- Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
- Other Notes: Sales restrictions may apply.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
grade: pharmaceutical primary standard
API family: simvastatin
manufacturer/tradename: USP
technique(s): HPLC: suitablegas chromatography (GC): suitable
mp: 127-132 °C (lit.)
application(s): pharmaceutical (small molecule)
format: neat
SMILES string: [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
InChI: 1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI key: RYMZZMVNJRMUDD-HGQWONQESA-N
grade:
pharmaceutical primary standard
API family:
simvastatin
manufacturer/tradename:
USP
technique(s):
HPLC: suitablegas chromatography (GC): suitable
mp:
127-132 °C (lit.)
application(s):
pharmaceutical (small molecule)
format:
neat
SMILES string:
[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
InChI:
1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI key:
RYMZZMVNJRMUDD-HGQWONQESA-N
grade: pharmaceutical primary standard
API family: sisomicin
manufacturer/tradename: USP
technique(s): __
mp: __
application(s): pharmaceutical (small molecule)
format: neat
SMILES string: OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3OC(CN)=CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6OC(CN)=CC[C@H]6N)[C@@H]5O
InChI: 1S/2C19H37N5O7.5H2O4S/c2*1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;5*1-5(2,3)4/h2*3,9-18,24-27H,4-7,20-23H2,1-2H3;5*(H2,1,2,3,4)/t2*9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+;;;;;/m11...../s1
InChI key: CIKNYWFPGZCHDL-ZHFUJENKSA-N
grade:
pharmaceutical primary standard
API family:
sisomicin
manufacturer/tradename:
USP
technique(s):
__
mp:
__
application(s):
pharmaceutical (small molecule)
format:
neat
SMILES string:
OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3OC(CN)=CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6OC(CN)=CC[C@H]6N)[C@@H]5O
InChI:
1S/2C19H37N5O7.5H2O4S/c2*1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;5*1-5(2,3)4/h2*3,9-18,24-27H,4-7,20-23H2,1-2H3;5*(H2,1,2,3,4)/t2*9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+;;;;;/m11...../s1
InChI key:
CIKNYWFPGZCHDL-ZHFUJENKSA-N
grade: pharmaceutical primary standard
API family: sibutramine
manufacturer/tradename: USP
technique(s): __
mp: __
application(s): pharmaceutical (small molecule)
format: neat
SMILES string: __
InChI: __
InChI key: __
grade:
pharmaceutical primary standard
API family:
sibutramine
manufacturer/tradename:
USP
technique(s):
__
mp:
__
application(s):
pharmaceutical (small molecule)
format:
neat
SMILES string:
__
InChI:
__
InChI key:
__
grade: pharmaceutical primary standard
API family: sibutramine
manufacturer/tradename: USP
technique(s): __
mp: __
application(s): pharmaceutical (small molecule)
format: neat
SMILES string: __
InChI: __
InChI key: __
grade:
pharmaceutical primary standard
API family:
sibutramine
manufacturer/tradename:
USP
technique(s):
__
mp:
__
application(s):
pharmaceutical (small molecule)
format:
neat
SMILES string:
__
InChI:
__
InChI key:
__