94873

4-Hydroxytamoxifen

(E) and (Z) isomers (50:50), analytical standard

Manufacturer: Supelco

CAS Number: 68392-35-8

Synonym(S): 4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol, 4-OHT, cis/trans-4-Hydroxytamoxifen

Select a Size

Pack Size SKU Availability Price
10 MG 94873-10-MG In Stock ₹ 18,694.78

94873 - 10 MG

₹ 18,694.78

In Stock

Quantity

1

Base Price: ₹ 18,694.78

GST (18%): ₹ 3,365.06

Total Price: ₹ 22,059.84

grade

analytical standard

Quality Level

100

Assay

≥97.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitablegas chromatography (GC): suitable

impurities

≤5.0% water

application(s)

forensics and toxicologypharmaceutical (small molecule)

format

neat

SMILES string

CC\C(c1ccccc1)=C(/c2ccc(O)cc2)c3ccc(OCCN(C)C)cc3.CC\C(c4ccccc4)=C(\c5ccc(O)cc5)c6ccc(OCCN(C)C)cc6

InChI

1S/2C26H29NO2/c2*1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h2*5-17,28H,4,18-19H2,1-3H3/b26-25+;26-25-

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Description

  • General description: 4-Hydroxytamoxifen is a first generation, selective estrogen receptor modulator (SERM) that functions as an antagonist in breast cancer cells but can display estrogen-like activities in the uterus and bone.[1]
  • Application: 4-Hydroxytamoxifen may be used as a reference standard in the determination of 4-hydroxythmoxifen in plasma samples using high-performance liquid chromatography with fluorescence detection (HPLC).[2]
  • Biochem/physiol Actions: Metabolite of the chemotherapeutic drug tamoxifen, exhibiting more potent estrogen agonist/antagonist activity than the parent drug. Also active as intra-membranous inhibitor of lipid peroxidation.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332,H315,H319,H361fd

Precautionary Statements

P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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analytical standard

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Assay:
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limited shelf life, expiry date on the label

technique(s):
HPLC: suitablegas chromatography (GC): suitable

impurities:
≤5.0% water

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forensics and toxicologypharmaceutical (small molecule)

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CC\C(c1ccccc1)=C(/c2ccc(O)cc2)c3ccc(OCCN(C)C)cc3.CC\C(c4ccccc4)=C(\c5ccc(O)cc5)c6ccc(OCCN(C)C)cc6

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1S/2C26H29NO2/c2*1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h2*5-17,28H,4,18-19H2,1-3H3/b26-25+;26-25-

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