Phosphate Phosphorus Standard for IC

Description

• General description: This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to SI unit kg and measured against primary material from an NMI, e.g. NIST. Certified content incl. uncertainty and expiry date are given on the certificate. Download your certificate at: http://www.sigma-aldrich.com.
• Application: Quantitative determination of topiramate in human plasma: A method employing liquid chromatography tandem mass spectrometry was developed to quantitatively determine topiramate in human plasma, highlighting the precision and applicability of using advanced analytical techniques for therapeutic drug monitoring in clinical settings (Popov et al., 2013).Dried blood spots technique for topiramate: The development and validation of a dried blood spots technique for quantitative determination of topiramate using liquid chromatography-tandem mass spectrometry was conducted. This method offers a minimally invasive sample collection option that could improve therapeutic drug monitoring for patients on topiramate (Popov et al., 2013).Therapeutic drug monitoring by LC-MS/MS: A study described a robust method for the therapeutic drug monitoring of topiramate using liquid chromatography-tandem mass spectrometry (LC-MS/MS), providing essential data on drug stability and concentration levels necessary for effective patient management (Matar, 2010).
• Linkage: Visit the IC Portal to learn more
• Analysis Note: 1000 mg/L P as phosphate in water, prepared with high purity Na2HPO4 and water
• Other Notes: For a complete product listing of our TraceCERT range of CRMs for ICP and AAS, technical information and example certificates please visit our inorganic TraceCERT website
• Legal Information: TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany