Description

• General description: Dimethyl sulfoxide is a free radical scavenger and a cryopreservant. It elicits protective effect in double stranded breaks(DSBs).[1] Dimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination.[2] As a PCR cosolvent, DMSO may help improve yields, especially in long PCR.[3]
• Application: Dimethyl sulfoxide has been used as a component of polymerase chain reaction (PCR) mixture[4] and as PCR facilitator.[2][5]
• Caution: Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.
• Other Notes: For information on dimethyl sulfoxide miscibility, please visit the following link:Dimethyl Sulfoxide Miscibility/Immiscibility Table