P6503

Pilocarpine hydrochloride

≥99% (titration), powder, muscarinic acetylcholine receptor agonist

Manufacturer: Sigma Aldrich

CAS Number: 54-71-7

Synonym(S): (3S,4R)-4,5-Dihydro-3-ethyl-4-(1-methyl-1H-imidazol-5-ylmethyl)-2(3H)-furanone hydrochloride

Select a Size

Pack Size SKU Availability Price
5 G P6503-5-G In Stock ₹ 13,098.25
10 G P6503-10-G In Stock ₹ 24,237.18
50 G P6503-50-G In Stock ₹ 78,589.50

P6503 - 5 G

₹ 13,098.25

In Stock

Quantity

1

Base Price: ₹ 13,098.25

GST (18%): ₹ 2,357.685

Total Price: ₹ 15,455.935

Quality Level

100

Assay

≥99% (titration)

form

powder

technique(s)

HPLC: suitablegas chromatography (GC): suitable

color

white

mp

202-205 °C (lit.)

solubility

H2O: 100 mg/mL

application(s)

forensics and toxicologyveterinary

relevant disease(s)

epilepsy

SMILES string

Cl.CC[C@H]1[C@H](COC1=O)Cc2cncn2C

Other Options

Image Product Name Manufacturer Price Range
11-100-2002
phyproof™ Pilocarpine hydrochloride, ≥95% (HPLC), MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 29,946.00
11-101-9245
Pilocarpine Hydrochloride Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 14,776.21
50-180-5063
Sigma Aldrich Fine Chemicals Biosciences Pilocarpine hydrochloride >=99% (titration), powder | 54-71-7 | MFCD00012722 | 50G
Sigma Aldrich Fine Chemicals Biosciences ₹ 1,51,441.20
PHR1493
Pilocarpine Hydrochloride
Supelco ₹ 12,935.88
1538902
Pilocarpine hydrochloride
Sigma Aldrich ₹ 47,326.90
PHL80370
Pilocarpine hydrochloride
Sigma Aldrich ₹ 30,623.93
AB54501
54-71-7 | (3S,4R)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride
A2B Chem ₹ 2,909.04 - ₹ 30,544.92

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Description

  • Application: Pilocarpine hydrochloride has been used to stimulate salivary secretions in mice.[1] It has also been used to induce status epilepticus(SE) in rat.[2][3]
  • Biochem/physiol Actions: Pilocarpine is alkaloid isolated from the shrub Pilocarpus species. It comprises imidazole ring and γ- lactone rings in its structure. It has cholinergic potential and it stimulates the parasympathetic system. Pilocarpine is also effective for treating glaucoma.[4] It stimulates ciliary muscle contraction by binding to muscarinic M3 receptors.[5] It is effective in treating corneal dryness in Sjogren′s syndrome.[6] It is a secretagogue, which improves salivary secretions in Xerostomia or a dry mouth condition in Sjogren′s syndrome patients[7] and in radiotherapy patients with head and neck carcinoma.[8]
  • Features and Benefits: This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
  • Caution: Hygroscopic, light sensitive
  • Other Notes: Shelf life of the powder is at least five years.

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H300 + H330

Precautionary Statements

P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

WGK

WGK 3

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H2O: 100 mg/mL

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forensics and toxicologyveterinary

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Cl.CC[C@H]1[C@H](COC1=O)Cc2cncn2C

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