Description

• General description: Aspirin (Acetyl Salicylic Acid) is a cyclo-oxygenase inhibitor[1] and an antiplatelet agent, widely used for the secondary preventions of heart attack and stroke.[2]Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
• Application: Aspirin (Acetyl Salicylic Acid) may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations[2] using spectrophotometric technique[2] and reversed-phase high-performance liquid chromatography technique.[1]
• Biochem/physiol Actions: Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.
• Analysis Note: These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
• Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
• Footnote: To see an example of a Certificate of Analysis for this material enter LRAB7669 in the slot below. This is an example certificate only and may not be the lot that you receive.