Description

• General description: Ammonium acetate (NH4CH3CO2, NH4OAc) is a water-soluble, hygroscopic ammonium salt. It is an eco-friendly and inexpensive compound that can be prepared by reacting glacial acetic acid with ammonia or ammonium carbonate. It is used as a catalyst as well as a source of ammonia in organic synthesis.
• Application: Ammonium acetate can be used as a reactant as well as a catalyst in the synthesis of:       1,3-oxazine derivatives by three-component condensation reaction with 2-naphthol and aromatic aldehydes.       Symmetrical terpyridine derivatives by treating with aromatic aldehydes and ethyl cyanoacetate.      Isoquinolines, furopyridines, and thienopyridines via Pd-catalyzed sequential coupling-imination-annulation reactions of ortho-bromoarylaldehydes and terminal alkynes.It can also be used as a nitrogen source to synthesize benzoxazole derivatives via multicomponent condensation reaction with catechols, and various aldehydes in the presence of Fe(III)−salen complex as a catalyst.
• Features and Benefits: NH4OAc is an eco-friendly, shelf-stable, and safe reagent.