646547
Tris(2-carboxyethyl)phosphine hydrochloride solution
0.5 M, pH 7.0(aqueous solution; pH was adjusted with ammonium hydroxide)
Manufacturer: Supelco
CAS Number: 51805-45-9
Synonym(S): TCEP
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 X 1 ML | 646547-10-X-1-ML | In Stock | ₹ 14,516.33 |
646547 - 10 X 1 ML
In Stock
Quantity
1
Base Price: ₹ 14,516.33
GST (18%): ₹ 2,612.939
Total Price: ₹ 17,129.269
Quality Level
200
concentration
0.5 M
refractive index
n20/D 1.367
pH
7.0(aqueous solution; pH was adjusted with ammonium hydroxide)
density
1.041 g/mL at 25 °C
SMILES string
Cl.OC(=O)CCP(CCC(O)=O)CCC(O)=O
InChI
1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
InChI key
PBVAJRFEEOIAGW-UHFFFAOYSA-N
Other Options
Related Products
Description
- General description: It belongs to the trialkylphosphine class.[1]
- Application: Tris (2-carboxyethyl) phosphine (TCEP) can be used in several downstream applications including SDS-PAGE, mass spectrometry, labeling with cysteine specific tags, and modification of cysteine containing compounds. It prevents oxidation of protein samples, which makes it a useful buffer component as it helps to preserve enzymatic activity.[4][5][6] It has been used in the reduction and measurement of glutathione.[7]
- Biochem/physiol Actions: As a non-mercaptan reducing agent, it avoids the toxicity inherent in thiol-containing compounds. It is capable of disrupting the botulinum neurotoxin B heavy-chain/light-chain complex that is held together by a single disulfide bond, and that is responsible for endocytosis, and ultimately the toxicity, of the toxin. Since disulfide-coupled subunits are characteristic of many toxins (e.g., ricin, snake venom, and all BoNT serotypes), it may be useful as a rescue prophylactic in cases of toxin administration.[11]
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
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Quality Level: 200
concentration: 0.5 M
refractive index: n20/D 1.367
pH: 7.0(aqueous solution; pH was adjusted with ammonium hydroxide)
density: 1.041 g/mL at 25 °C
SMILES string: Cl.OC(=O)CCP(CCC(O)=O)CCC(O)=O
InChI: 1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
InChI key: PBVAJRFEEOIAGW-UHFFFAOYSA-N
Quality Level:
200
concentration:
0.5 M
refractive index:
n20/D 1.367
pH:
7.0(aqueous solution; pH was adjusted with ammonium hydroxide)
density:
1.041 g/mL at 25 °C
SMILES string:
Cl.OC(=O)CCP(CCC(O)=O)CCC(O)=O
InChI:
1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
InChI key:
PBVAJRFEEOIAGW-UHFFFAOYSA-N
Quality Level: 100
concentration: 1 M in H2O
refractive index: __
pH: __
density: 1.04 g/mL at 20 °C1.035 g/mL at 25 °C
SMILES string: O[C@H](CS)[C@H](O)CS
InChI: 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChI key: VHJLVAABSRFDPM-QWWZWVQMSA-N
Quality Level:
100
concentration:
1 M in H2O
refractive index:
__
pH:
__
density:
1.04 g/mL at 20 °C1.035 g/mL at 25 °C
SMILES string:
O[C@H](CS)[C@H](O)CS
InChI:
1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChI key:
VHJLVAABSRFDPM-QWWZWVQMSA-N
Quality Level: 100
concentration: __
refractive index: __
pH: __
density: __
SMILES string: OB(O)C1CCC1
InChI: 1S/C4H9BO2/c6-5(7)4-2-1-3-4/h4,6-7H,1-3H2
InChI key: MIUALDDWOKMYDA-UHFFFAOYSA-N
Quality Level:
100
concentration:
__
refractive index:
__
pH:
__
density:
__
SMILES string:
OB(O)C1CCC1
InChI:
1S/C4H9BO2/c6-5(7)4-2-1-3-4/h4,6-7H,1-3H2
InChI key:
MIUALDDWOKMYDA-UHFFFAOYSA-N
Quality Level: 100
concentration: __
refractive index: __
pH: __
density: __
SMILES string: Nc1cc(n[nH]1)-c2ccc(Br)cc2
InChI: 1S/C9H8BrN3/c10-7-3-1-6(2-4-7)8-5-9(11)13-12-8/h1-5H,(H3,11,12,13)
InChI key: FTCWIBNIYIEHDT-UHFFFAOYSA-N
Quality Level:
100
concentration:
__
refractive index:
__
pH:
__
density:
__
SMILES string:
Nc1cc(n[nH]1)-c2ccc(Br)cc2
InChI:
1S/C9H8BrN3/c10-7-3-1-6(2-4-7)8-5-9(11)13-12-8/h1-5H,(H3,11,12,13)
InChI key:
FTCWIBNIYIEHDT-UHFFFAOYSA-N