Description

• General description: 4-(Dimethylamino)pyridine (DMAP) is a catalyst for esterification and amidation reagents [1,2,3]. Literature references[1] S. S. Wang, et al. (1981) Int. J. Peptide Protein Res., 18, 459. [2] J.-P. Gamet, et al. (1984) Tetrahedron, 40, 1995. [3] K. Takeda, et al. (1991) Synthesis, 1991, 689.
• Application: Copolymerization of β‐butyrolactones using DMAP as initiator: This research focuses on the use of DMAP in the ring-opening polymerization of β‐butyrolactones, analyzing its efficiency as a catalyst (Palenzuela et al., 2024).Halogen-Bond-Promoted Direct Cross-Coupling: This article details the use of DMAP in a catalytic process for the cross-coupling of alkyl bromides with coumarins, emphasizing its role under light illumination (Guo et al., 2024).Enantiospecific Analysis of Carboxylic Acids: Discusses the superior efficacy of DMAP compared to other catalysts like Et3N in the enantiospecific analysis of carboxylic acids (Mo et al., 2024).
• Linkage: Replaces: 01-62-0004
• Analysis Note: Colour (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testSolubility (1 mmole in 2 ml DMF): clearly solubleAssay (GC, area%): ≥ 99.0 % (a/a)Melting range (lower value): ≥ 110 °CMelting range (upper value): ≤ 113 °C
• Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany