Cyclosporine
United States Pharmacopeia (USP) Reference Standard
Manufacturer: Sigma Aldrich
CAS Number: 59865-13-3
Synonym(S): Cyclosporin A, Antibiotic S 7481F1, Cyclosporine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 1158504-50-MG | In Stock | ₹ 1,51,182.00 |
1158504 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 1,51,182.00
GST (18%): ₹ 27,212.76
Total Price: ₹ 1,78,394.76
grade
pharmaceutical primary standard
API family
cyclosporine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
SMILES string
CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C
InChI
1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
InChI key
PMATZTZNYRCHOR-CGLBZJNRSA-N
Gene Information
human ... PPIA(5478)
Other Options
Related Products
Description
- General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
- Application: Cyclosporine USP reference standard is meant for specified quality tests and assays.Also used to prepare standard solutions for the assay, identification and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):Cyclosporine[1]Cyclosporine Injection[2]Cyclosporine Oral Solution[3]Cyclosporine Capsules[4]Cyclosporine Compounded Ophthalmic Solution, Veterinary[5]
- Biochem/physiol Actions: A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.
- Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
- Other Notes: Sales restrictions may apply.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Repr. 1B
WGK
WGK 3
Compare Similar Items
Show Difference
grade: pharmaceutical primary standard
API family: cyclosporine
manufacturer/tradename: USP
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: −20°C
SMILES string: CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C
InChI: 1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
InChI key: PMATZTZNYRCHOR-CGLBZJNRSA-N
Gene Information: human ... PPIA(5478)
grade: __
API family: __
manufacturer/tradename: __
application(s): __
format: __
storage temp.: __
SMILES string: Cc1cccc(C)c1Br
InChI: 1S/C8H9Br/c1-6-4-3-5-7(2)8(6)9/h3-5H,1-2H3
InChI key: MYMYVYZLMUEVED-UHFFFAOYSA-N
Gene Information: __
grade: __
API family: __
manufacturer/tradename: Roche
application(s): __
format: __
storage temp.: __
SMILES string: __
InChI: __
InChI key: __
Gene Information: __
