1205003

Diltiazem hydrochloride

United States Pharmacopeia (USP) Reference Standard

Manufacturer: Sigma Aldrich

CAS Number: 33286-22-5

Synonym(S): (+)-cis-Diltiazem hydrochloride, (2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride, CRD-401

Select a Size

Pack Size SKU Availability Price
200 MG 1205003-200-MG In Stock ₹ 40,756.13

1205003 - 200 MG

₹ 40,756.13

In Stock

Quantity

1

Base Price: ₹ 40,756.13

GST (18%): ₹ 7,336.103

Total Price: ₹ 48,092.233

grade

pharmaceutical primary standard

API family

diltiazem

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O

InChI

1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1

InChI key

HDRXZJPWHTXQRI-BHDTVMLSSA-N

Gene Information

human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)

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Description

  • General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
  • Application: Exploring the Effectiveness of Carboxymethylated and Crosslinked Albizia procera Gum in Diltiazem Hydrochloride Matrix Tablets: A Comparative Analysis. This study investigates the potential of carboxymethylated and crosslinked Albizia procera gum for use in sustained-release matrix tablets containing Diltiazem hydrochloride, highlighting its viability in pharmaceutical applications (Mukherjee S, Khanam J, 2024). Dietary gallic acid as an antioxidant: A review of its food industry applications, health benefits, bioavailability, nano-delivery systems, and drug interactions. While primarily focused on gallic acid, this review mentions Diltiazem hydrochloride in the context of drug interactions and its implications in food safety and health (Xiang Z et al., 2024). Dual stimuli-responsive and sustained drug delivery NanoSensoGel formulation for prevention of cisplatin-induced ototoxicity. This research presents a novel NanoSensoGel that could be adapted for Diltiazem hydrochloride, enhancing drug delivery efficiency in clinical settings (Thakur NS et al., 2024). A novel potentiometric sensor based on ZnO decorated polyaniline/coal nanocomposite for diltiazem determination. This study develops a new sensor for the precise measurement of Diltiazem levels in pharmaceutical formulations, which is crucial for quality control and regulatory compliance (El Sayed GA et al., 2023). The Effect of Topical Nifedipine versus Diltiazem on the Acute Anal Fissure: A Randomized Clinical Trial. This clinical trial evaluates the effectiveness of Diltiazem hydrochloride in treating acute anal fissures, providing evidence of its beneficial applications in proctological disorders (Momayez Sanat Z et al., 2023).
  • Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
  • Other Notes: Sales restrictions may apply.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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grade:
pharmaceutical primary standard

API family:
diltiazem

manufacturer/tradename:
USP

application(s):
pharmaceutical (small molecule)

format:
neat

SMILES string:
Cl.COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O

InChI:
1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1

InChI key:
HDRXZJPWHTXQRI-BHDTVMLSSA-N

Gene Information:
human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)

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NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O

InChI:
1S/C6H6N2O4S/c7-13(11,12)6-3-1-5(2-4-6)8(9)10/h1-4H,(H2,7,11,12)

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QWKKYJLAUWFPDB-UHFFFAOYSA-N

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O.O.[Ca++].[O-]S([O-])(=O)=O

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__

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__