MS calibration solution

Description

• Application: Therapeutic drug monitoring in oncology: MS calibration solutions are crucial in the development and validation of ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) methods for the quantitation of pralsetinib in human plasma and cerebrospinal fluid, enhancing therapeutic drug monitoring in oncology (Zhao et al., 2024).Continuous homogenous liquid phase microextraction: In the analysis of aliphatic amines in urine, a new microextraction technique utilizing MS calibration solutions based on in-situ preparation of deep eutectic solvent demonstrates advancements in gas chromatography-mass spectrometry (GC-MS) applications (Shagaghipour et al., 2024).Detection of toxic substances in pharmaceuticals: MS calibration solutions aid in the selective quantitation of ethylene and diethylene glycol in pediatric syrups using gas chromatography-tandem mass spectrometry, ensuring product safety and compliance with pharmaceutical standards (Altamimy et al., 2024).Bioequivalence studies: The application of MS calibration solutions in LC-MS/MS methods facilitates the rapid detection and validation of vonoprazan fumarate in human plasma, critical for conducting bioequivalence studies in clinical pharmacology (Chen et al., 2024).Electrochemical detection of heavy metals: MS calibration solutions are utilized in modifying carbon-fiber microelectrodes with gold nanoparticles for the electrochemical detection of cadmium via fast-scan cyclic voltammetry, highlighting their utility in environmental monitoring and public health safety (Manring et al., 2024).