30450

Daunorubicin hydrochloride

≥90% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 23541-50-6

Synonym(S): Daunomycin hydrochloride

Select a Size

Pack Size SKU Availability Price
5 MG 30450-5-MG In Stock ₹ 15,035.93
25 MG 30450-25-MG In Stock ₹ 34,196.18

30450 - 5 MG

₹ 15,035.93

In Stock

Quantity

1

Base Price: ₹ 15,035.93

GST (18%): ₹ 2,706.467

Total Price: ₹ 17,742.397

biological source

synthetic

Quality Level

200

Assay

≥90% (HPLC)

form

powder

color

red to deep red

antibiotic activity spectrum

neoplastics

Mode of action

DNA synthesis | interferes

storage temp.

2-8°C

SMILES string

Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O

InChI

1S/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3;1H/t10-,14-,16-,17-,22+,27-;/m0./s1

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Description

  • General description: Chemical structure: aminoglycoside
  • Application: Daunorubicin hydrochloride is used in photostability[1], antileukemic[2], and drug metabolism studies[3].
  • Biochem/physiol Actions: On binding to DNA, daunomycin intercalates, with its daunosamine residue directed toward the minor groove. Daunomycin effectively binds to every 3 base pairs which causes unwinding.
  • Packaging: 5 mg, 25 mg
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Store under inert gas.

SAFETY INFORMATION

Pictograms

GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H341,H351,H360FD

Precautionary Statements

P202 - P264 - P280 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2 - Muta. 2 - Repr. 1B

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O

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