42966
12-Hydroxy-octadecanoicacid polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl)
Manufacturer: Sigma Aldrich
CAS Number: 70142-34-6
Synonym(S): HS 15, Macrogol (15)-hydroxystearate, Polyethylene glycol (15)-hydroxystearate, Polyoxyethylated 12-hydroxystearic acid, Solutol® HS 15
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 KG | 42966-1-KG | In Stock | ₹ 31,779.30 |
42966 - 1 KG
In Stock
Quantity
1
Base Price: ₹ 31,779.30
GST (18%): ₹ 5,720.274
Total Price: ₹ 37,499.574
description
non-ionic
Quality Level
100
form
paste
composition
free macrogoly% (27.0 - 39.0 g/100g (%))
impurities
acetic acid (≤ 0.5 g/100g (%)) water (≤ 0.5 g/100g (%))≤0.05% acetic acid≤0.05% water≤1 mg/kg ethylene oxide ((ppm))≤1 mg/kg ethylene oxide≤1 mg/kg nickel ((ppm))≤1 mg/kg nickle≤10 mg/kg dioxane ((ppm))≤10 mg/kg dioxane≤10 mg/kg heavy metals≤620 mg/kg Diethylene glycol≤620 mg/kg diethylene glycol ((ppm))≤620 mg/kg ethylene glycol ((ppm))≤620 mg/kg ethylene glycol<10 mg/kg heavy metals ((ppm))
ign. residue
(≤ 0.3 g/100g (%))
pH
5.0-7.0 (1 g/10 mL in H2O)
mp
25 - 30 °C (77 - 86 °F)
acid value
≤1.0 mg KOH/g
hydroxyl value
90‑110 mg KOH/g
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Kolliphor HS 15 | 70142-34-6 | 1 kg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 39,828.18 | |
 | Polyoxyl 15 hydroxystearate | Sigma Aldrich | ₹ 47,552.40 | |
 | 70142-34-6 | Octadecanoic acid, 12-hydroxy-, polymer with .alpha.-hydro-.omega.-hydroxypoly(oxy-1,2-ethanediyl) | A2B Chem | ₹ 941.16 - ₹ 18,395.40 |
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Description
- General description: 12-Hydroxy-octadecanoicacid polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl), a pH-independent non-ionic surfactant, is an effective solubilizer and emulsifying agent. It is soluble in aqueous media and polar organic solvents however it is not soluble in apolar solvents. Its structure has 12-hydroxystearic acid (lipophilic moiety) and polyethylene glycol (hydrophilic moiety).
- Application: 12-Hydroxy-octadecanoic acid polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) has been used:in dissolving dexamethasone (DEX) to intraperitoneally inject the mice to test its grip strength to measure the muscle forcein roflumilast preparation to treat rabbits and guinea pigs to study the mechanisms and pharmacological sensitivity of ozone-induced hypertussive responsesto dissolve finerenone for oral application in in vivo-studies
- Biochem/physiol Actions: 12-Hydroxy-octadecanoic acid polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) is mainly used as a solubilizer in parenteral and oral formulations. It is preferred for in vitro screening and in vivo efficacy studies of compounds. 12-Hydroxy-octadecanoic acid polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) is also used in ophthalmic, macromolecule, suppository, and protein formulations due to its solubilization characteristics and safety profiles. It can form micelles typically ranging from 10-15 nm. 12-Hydroxy-octadecanoic acid polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) can be used to develop micro-emulsion IV formulations.
- Other Notes: 12-Hydroxy-octadecanoic acid polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) is a non-ionic detergent obtained by reacting 15 moles of ethylene oxide with 1 mole of 12-hydroxy stearic acid.
- Legal Information: Solutol is a registered trademark of BASF SE
SAFETY INFORMATION
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description: non-ionic
Quality Level: 100
form: paste
composition: free macrogoly% (27.0 - 39.0 g/100g (%))
impurities: acetic acid (≤ 0.5 g/100g (%)) water (≤ 0.5 g/100g (%))≤0.05% acetic acid≤0.05% water≤1 mg/kg ethylene oxide ((ppm))≤1 mg/kg ethylene oxide≤1 mg/kg nickel ((ppm))≤1 mg/kg nickle≤10 mg/kg dioxane ((ppm))≤10 mg/kg dioxane≤10 mg/kg heavy metals≤620 mg/kg Diethylene glycol≤620 mg/kg diethylene glycol ((ppm))≤620 mg/kg ethylene glycol ((ppm))≤620 mg/kg ethylene glycol<10 mg/kg heavy metals ((ppm))
ign. residue: (≤ 0.3 g/100g (%))
pH: 5.0-7.0 (1 g/10 mL in H2O)
mp: 25 - 30 °C (77 - 86 °F)
acid value: ≤1.0 mg KOH/g
hydroxyl value: 90‑110 mg KOH/g
description:
non-ionic
Quality Level:
100
form:
paste
composition:
free macrogoly% (27.0 - 39.0 g/100g (%))
impurities:
acetic acid (≤ 0.5 g/100g (%)) water (≤ 0.5 g/100g (%))≤0.05% acetic acid≤0.05% water≤1 mg/kg ethylene oxide ((ppm))≤1 mg/kg ethylene oxide≤1 mg/kg nickel ((ppm))≤1 mg/kg nickle≤10 mg/kg dioxane ((ppm))≤10 mg/kg dioxane≤10 mg/kg heavy metals≤620 mg/kg Diethylene glycol≤620 mg/kg diethylene glycol ((ppm))≤620 mg/kg ethylene glycol ((ppm))≤620 mg/kg ethylene glycol<10 mg/kg heavy metals ((ppm))
ign. residue:
(≤ 0.3 g/100g (%))
pH:
5.0-7.0 (1 g/10 mL in H2O)
mp:
25 - 30 °C (77 - 86 °F)
acid value:
≤1.0 mg KOH/g
hydroxyl value:
90‑110 mg KOH/g
description: __
Quality Level: 100
form: lyophilized
composition: __
impurities: ≤1.0 EU/μg Endotoxin (EU/μg leptin)
ign. residue: __
pH: __
mp: __
acid value: __
hydroxyl value: __
description:
__
Quality Level:
100
form:
lyophilized
composition:
__
impurities:
≤1.0 EU/μg Endotoxin (EU/μg leptin)
ign. residue:
__
pH:
__
mp:
__
acid value:
__
hydroxyl value:
__
description: __
Quality Level: 100
form: powder
composition: __
impurities: ≤150.0 ppm Trace Rare Earth Analysis
ign. residue: __
pH: __
mp: 850 °C (lit.)
acid value: __
hydroxyl value: __
description:
__
Quality Level:
100
form:
powder
composition:
__
impurities:
≤150.0 ppm Trace Rare Earth Analysis
ign. residue:
__
pH:
__
mp:
850 °C (lit.)
acid value:
__
hydroxyl value:
__
description: __
Quality Level: 100
form: powder
composition: __
impurities: ≤150.0 ppm Trace Rare Earth Analysis
ign. residue: __
pH: __
mp: 850 °C (lit.)
acid value: __
hydroxyl value: __
description:
__
Quality Level:
100
form:
powder
composition:
__
impurities:
≤150.0 ppm Trace Rare Earth Analysis
ign. residue:
__
pH:
__
mp:
850 °C (lit.)
acid value:
__
hydroxyl value:
__