D-070

N-Desmethylolanzapine-d8 dihydrochloride solution

100 μg/mL in acetonitrile: water (1:1) (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Manufacturer: Supelco

Synonym(S): N-Desmethylolanzapine-D8 dihydrochloride solution

Select a Size

Pack Size SKU Availability Price
1 ML D-070-1-ML In Stock ₹ 13,563.73

D-070 - 1 ML

₹ 13,563.73

In Stock

Quantity

1

Base Price: ₹ 13,563.73

GST (18%): ₹ 2,441.471

Total Price: ₹ 16,005.201

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in acetonitrile: water (1:1) (as free base)

technique(s)

gas chromatography (GC): suitableliquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

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Description

  • General description: A stable-labeled internal standard for use in LC/MS or GC/MS applications including clinical toxicology analysis, therapeutic drug monitoring, or isotope dilution methods. Desmethylolanzapine is the primary metabolite of olanzapine, marketed as the atypical antipsychotic Zyprexa® for the treatment of schizophrenia and bipolar disorder.
  • Application: Monitoring Metabolic Parameters in Schizophrenia: A study utilized plasma levels of olanzapine and its metabolite, N-desmethyl-olanzapine, to monitor metabolic parameters in patients with schizophrenia, providing a critical link between antipsychotic drug concentrations and metabolic health. This research supports the use of these biomarkers in clinical settings to optimize therapeutic strategies and manage side effects (Lu et al., 2018).Evaluating Clinical Efficacy in Schizophrenia: Another significant study applied plasma levels of olanzapine and N-desmethyl-olanzapine to assess clinical efficacy in schizophrenia patients. By correlating drug levels with therapeutic outcomes, this approach aids in personalized medicine, ensuring patients receive optimal dosages for effective treatment (Lu et al., 2016).
  • Legal Information: CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Pictograms

GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H302,H319

Precautionary Statements

P210 - P233 - P240 - P241 - P301 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

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Snap-N-Spike®/Snap-N-Shoot®

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Cerilliant®

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