E1753

(−)-Epicatechin

≥90% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 490-46-0

Synonym(S): (−)-cis-3,3′,4′,5,7-Pentahydroxyflavane, (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

Select a Size

Pack Size SKU Availability Price
1 G E1753-1-G In Stock ₹ 19,019.53
5 G E1753-5-G In Stock ₹ 77,626.08

E1753 - 1 G

₹ 19,019.53

In Stock

Quantity

1

Base Price: ₹ 19,019.53

GST (18%): ₹ 3,423.515

Total Price: ₹ 22,443.045

Quality Level

200

Assay

≥90% (HPLC)

form

powder

mp

240 °C (dec.) (lit.)

application(s)

metabolomicsvitamins, nutraceuticals, and natural products

SMILES string

O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1

InChI key

PFTAWBLQPZVEMU-UKRRQHHQSA-N

Gene Information

human ... BACE1(23621) , CYP1A2(1544)

Other Options

Image Product Name Manufacturer Price Range
11-101-4305
(-)-Epicatechin, ≥97% (HPLC), MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 52,063.26
50-178-7727
Sigma Aldrich Fine Chemicals Biosciences (-)-Epicatechin >=90% (HPLC) | 490-46-0 | MFCD00075648 | 1G
Sigma Aldrich Fine Chemicals Biosciences ₹ 21,277.06
50-178-7730
Sigma Aldrich Fine Chemicals Biosciences (−)-Epicatechin | 490-46-0 | MFCD00075648 | 5mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 21,486.68
68097
(−)-Epicatechin
Supelco ₹ 40,247.35
PHL89192
(−)-Epicatechin
Sigma Aldrich ₹ 40,517.98
03940590
Epicatechin
Sigma Aldrich ₹ 39,543.73
74873
(−)-Epicatechin
Supelco ₹ 23,836.65
E4018
(−)-Epicatechin
Sigma Aldrich ₹ 5,813.03 - ₹ 22,440.23
CS-3760
(-)-Epicatechin
ChemScene ₹ 1,368.96 - ₹ 35,421.84

Description

  • General description: (−)-Epicatechin (EC) belongs to the group of flavanols and is abundantly present in cacao and cacao products.[1] The chemical structure of EC includes an oxygenated heterocycle with a 4-hydroxyl group linked with two aromatic rings.[1]
  • Application: (−)-Epicatechin (EC) has been used:as an antioxidant to downregulate nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidase and improve insulin sensitivity in in vivo (high fat-fed mice) and in vitro (HepG2 cells) studies[2]to study its effect on blood pressure, nitric oxide synthase (NOS) activity and anxiety-like behavior on borderline hypertensive rat (BHR) models[3]to test its effect on neuronal survival in the hippocampus of middle-aged rats on swimming training, under oxidative stress[4] to study its antioxidant activity in dark chocolate[5]as a characteristic compound in polyphenols analysis[6]
  • Biochem/physiol Actions: Epicatechin enhances the skeletal muscle structure in heart failure patients and minimizes cardiometabolic risks. It can be used for treating sarcopenia. Epicatechin reduces myostatin and β-galactosidase and increases the level of markers of muscle growth.[7]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quality Level:
200

Assay:
≥90% (HPLC)

form:
powder

mp:
240 °C (dec.) (lit.)

application(s):
metabolomicsvitamins, nutraceuticals, and natural products

SMILES string:
O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI:
1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1

InChI key:
PFTAWBLQPZVEMU-UKRRQHHQSA-N

Gene Information:
human ... BACE1(23621) , CYP1A2(1544)

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