I1286

Icariin

≥94% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 489-32-7

Synonym(S): 4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside

Select a Size

Pack Size SKU Availability Price
100 MG I1286-100-MG In Stock ₹ 15,598.83
1 G I1286-1-G In Stock ₹ 61,529.30

I1286 - 100 MG

₹ 15,598.83

In Stock

Quantity

1

Base Price: ₹ 15,598.83

GST (18%): ₹ 2,807.789

Total Price: ₹ 18,406.619

Quality Level

100

Assay

≥94% (HPLC)

color

light yellow to yellow

solubility

DMSO: 50 mg/mL, clear, colorless to dark yellow

application(s)

metabolomicsvitamins, nutraceuticals, and natural products

storage temp.

room temp

SMILES string

COc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2

InChI

1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1

InChI key

TZJALUIVHRYQQB-XLRXWWTNSA-N

Other Options

Image Product Name Manufacturer Price Range
50-824-5
Selleck Chemical LLC Icariin 100mg 489-32-7
Selleck Chemical LLC ₹ 12,320.64
11-101-4302
Icariin, ≥95% (HPLC), MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 38,245.32
50-176-2741
Sigma Aldrich Fine Chemicals Biosciences Icariin >=94% (HPLC) | 489-32-7 | MFCD00210516 | 100MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 17,503.86
56601
Icariin
Supelco ₹ 33,341.00
PHL89714
Icariin
Sigma Aldrich ₹ 39,630.33

Description

  • General description: Icariin is a prenylated flavonol and the major bioactive compound found in Epimedium herb.[1]
  • Application: Icariin has been used:in the preparation of topical treatment to determine its effects on the improvement of cutaneous wound healing in rats[2]to test its analgesic effects on lower back pain (LBP) in rats[3]as a potential treatment in osteoporosis condition in rats[4]to study its effects on palmitate (PA)-induced insulin resistance in skeletal muscle C2C12 myotubes[5]as a neuroprotective agent to study its effects on amyloid-β (Aβ)-induced neuronal insulin resistance in human neuroblastoma SK-N-MC cells[6]
  • Biochem/physiol Actions: Icariin is a potent neuroprotective agent in neurodegenerative disorders and other disorders affecting the nervous system.[1] It elicits anti-aging properties in unfertilized oocytes against age-related damage.[7] Icariin exerts anti-inflammatory and antifibrotic properties aiding protection in chronic kidney disease (CKD)-associated renal fibrosis in mouse model.[8] It also serves as an excellent antidiabetic[9] and anti-atherosclerotic agent.[10] Icariin is an excellent anti-cancer agent.[1]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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100

Assay:
≥94% (HPLC)

color:
light yellow to yellow

solubility:
DMSO: 50 mg/mL, clear, colorless to dark yellow

application(s):
metabolomicsvitamins, nutraceuticals, and natural products

storage temp.:
room temp

SMILES string:
COc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2

InChI:
1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1

InChI key:
TZJALUIVHRYQQB-XLRXWWTNSA-N

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[H][C@@]12CC[C@@](C)([C@H](O)C1)C2(C)C

InChI:
1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8-,10+/m1/s1

InChI key:
DTGKSKDOIYIVQL-MRTMQBJTSA-N