P7262

Plumbagin from Plumbago indica

Manufacturer: Sigma Aldrich

CAS Number: 481-42-5

Synonym(S): 5-Hydroxy-2-methyl-1,4-naphthoquinone

Select a Size

Pack Size SKU Availability Price
100 MG P7262-100-MG In Stock ₹ 3,171.73
250 MG P7262-250-MG In Stock ₹ 6,148.60
1 G P7262-1-G In Stock ₹ 16,941.13

P7262 - 100 MG

₹ 3,171.73

In Stock

Quantity

1

Base Price: ₹ 3,171.73

GST (18%): ₹ 570.911

Total Price: ₹ 3,742.641

biological source

Plumbago indica

Quality Level

200

form

powder

color

faint orange to dark orange

mp

76-78 °C (lit.)

storage temp.

−20°C

SMILES string

CC1=CC(C2=C(C1=O)C=CC=C2O)=O

InChI

1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3

InChI key

VCMMXZQDRFWYSE-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
50-185-8281
Sigma Aldrich Fine Chemicals Biosciences Plumbagin from Plumbago indica | 481-42-5 | MFCD00001682 | 1G
Sigma Aldrich Fine Chemicals Biosciences ₹ 18,551.97
50-193-3845
Medchemexpress LLC HY-N1497 50mg Medchemexpress, Plumbagin CAS:481-42-5 Purity:>98%
Medchemexpress LLC ₹ 8,534.61
50-185-8282
Sigma Aldrich Fine Chemicals Biosciences Plumbagin from Plumbago indica | 481-42-5 | MFCD00001682 | 250MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 7,092.92
PHL80267
Plumbagin
Sigma Aldrich ₹ 30,623.93
AB78411
481-42-5 | 5-hydroxy-2-methyl-1,4-dihydronaphthalene-1,4-dione
A2B Chem ₹ 2,823.48 - ₹ 7,187.04

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Description

  • General description: Plumbagin is a bioactive naphthoquinone present majorly in Plumbago indica L.[1] It is a quinoid and is also derived from the roots of Plumbago zeylanica roots.[2]
  • Application: Plumbagin from Plumbago indica has been used: as a reactive oxygen species agent (ROS) to induce cytotoxicity in mouse embryonic fibroblasts[3]as an oxidative stress inducer to generate superoxide anion in Saccharomyces cerevisiae[4]as a reference standard in thin layer chromatography and in spectrophotometric analysis for quantification of plumbagin in Plumbago auriculate samples[5]
  • Biochem/physiol Actions: Plumbagin exhibits various pharmacological activities including antimicrobial, anticancer,[1] anti-atherosclerotic, antidiabetic, anti-inflammatory, hypolipidemic, and neuroprotective activities.[6] It inhibits the signal transducer and activator of transcription 3 (STAT3) signaling and halts the proliferation of esophageal squamous cell carcinoma (ESCC).[2] Plumbagin elicits protective antioxidative functionality in 4-nitroquinoline-N-oxide (NQNO) induced stress in lymphoma.[7] Plumbagin in a nanoemulsion formulation has antiproliferative effect towards prostate cancer.[6]

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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P7262

--


biological source:
Plumbago indica

Quality Level:
200

form:
powder

color:
faint orange to dark orange

mp:
76-78 °C (lit.)

storage temp.:
−20°C

SMILES string:
CC1=CC(C2=C(C1=O)C=CC=C2O)=O

InChI:
1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3

InChI key:
VCMMXZQDRFWYSE-UHFFFAOYSA-N

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synthetic (organic)

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__

InChI:
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InChI key:
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Sigma Aldrich

P7280

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synthetic (organic)

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__

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SMILES string:
Cl[H].Cl[H].Nc1ccccc1N

InChI:
1S/C6H8N2.2ClH/c7-5-3-1-2-4-6(5)8;;/h1-4H,7-8H2;2*1H

InChI key:
RIIWUGSYXOBDMC-UHFFFAOYSA-N