PHL80506
Nitidine chloride
phyproof® Reference Substance
Manufacturer: Sigma Aldrich
CAS Number: 13063-04-2
Synonym(S): 2,3-Dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride, NSC 146397
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 MG | PHL80506-10-MG | In Stock | ₹ 48,788.28 |
PHL80506 - 10 MG
In Stock
Quantity
1
Base Price: ₹ 48,788.28
GST (18%): ₹ 8,781.89
Total Price: ₹ 57,570.17
grade
primary reference standard
product line
phyproof® Reference Substance
Assay
≥98.0% (HPLC)
manufacturer/tradename
PhytoLab
format
neat
SMILES string
C[N+]1=CC2=CC(OC)=C(OC)C=C2C3=CC=C4C=C5C(OCO5)=CC4=C31.[Cl-]
InChI
1S/C21H18NO4.ClH/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22;/h4-10H,11H2,1-3H3;1H/q+1;/p-1
InChI key
QLDAACVSUMUMOR-UHFFFAOYSA-M
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Medchem Express / Nitidine (chloride) / 5mg / 533802691 / HY-N0498 / / 13063-04-2 / MFCD01659688 / 383.830 / C21H18ClNO4 | eMolecules | ₹ 7,556.66 |
Related Products
Description
- General description: This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
- Biochem/physiol Actions: Nitidine chloride is a natural product with anti-cancer activity. Its mechanism of action likely involves several pathways. Nitidine chloride has been found to inhibit topoisomerase I and topoisomerase II, induce cell apoptosis by activation of the caspase-dependent pathway, suppress c-Src/FAK associated signaling pathways and suppress Janus kinase 2/STAT3 signaling and the expression of STAT3-dependent target genes, including cyclin D1, Bcl-xL, and VEGF. Nitidine chloride has also been found to have anti-malaria activity.
- Legal Information: phyproof is a registered trademark of PhytoLab GmbH & Co. KG
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
grade: primary reference standard
product line: phyproof® Reference Substance
Assay: ≥98.0% (HPLC)
manufacturer/tradename: PhytoLab
format: neat
SMILES string: C[N+]1=CC2=CC(OC)=C(OC)C=C2C3=CC=C4C=C5C(OCO5)=CC4=C31.[Cl-]
InChI: 1S/C21H18NO4.ClH/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22;/h4-10H,11H2,1-3H3;1H/q+1;/p-1
InChI key: QLDAACVSUMUMOR-UHFFFAOYSA-M
grade:
primary reference standard
product line:
phyproof® Reference Substance
Assay:
≥98.0% (HPLC)
manufacturer/tradename:
PhytoLab
format:
neat
SMILES string:
C[N+]1=CC2=CC(OC)=C(OC)C=C2C3=CC=C4C=C5C(OCO5)=CC4=C31.[Cl-]
InChI:
1S/C21H18NO4.ClH/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22;/h4-10H,11H2,1-3H3;1H/q+1;/p-1
InChI key:
QLDAACVSUMUMOR-UHFFFAOYSA-M
grade: primary reference standard
product line: phyproof® Reference Substance
Assay: ≥95.0% (HPLC)
manufacturer/tradename: PhytoLab
format: __
SMILES string: CC(=O)OC1CC(=O)OC(C)(C)[C@@H]2CC(=O)[C@]3(C)[C@H](CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@@]345)c6ccoc6)[C@@]12C
InChI: 1S/C28H34O9/c1-14(29)34-19-12-20(31)36-24(2,3)17-11-18(30)27(6)16(26(17,19)5)7-9-25(4)21(15-8-10-33-13-15)35-23(32)22-28(25,27)37-22/h8,10,13,16-17,19,21-22H,7,9,11-12H2,1-6H3/t16-,17+,19?,21+,22-,25+,26-,27+,28-/m1/s1
InChI key: KPDOJFFZKAUIOE-BIYZDVJRSA-N
grade:
primary reference standard
product line:
phyproof® Reference Substance
Assay:
≥95.0% (HPLC)
manufacturer/tradename:
PhytoLab
format:
__
SMILES string:
CC(=O)OC1CC(=O)OC(C)(C)[C@@H]2CC(=O)[C@]3(C)[C@H](CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@@]345)c6ccoc6)[C@@]12C
InChI:
1S/C28H34O9/c1-14(29)34-19-12-20(31)36-24(2,3)17-11-18(30)27(6)16(26(17,19)5)7-9-25(4)21(15-8-10-33-13-15)35-23(32)22-28(25,27)37-22/h8,10,13,16-17,19,21-22H,7,9,11-12H2,1-6H3/t16-,17+,19?,21+,22-,25+,26-,27+,28-/m1/s1
InChI key:
KPDOJFFZKAUIOE-BIYZDVJRSA-N
grade: primary reference standard
product line: phyproof® Reference Substance
Assay: ≥95.0% (HPLC)
manufacturer/tradename: PhytoLab
format: __
SMILES string: O=C1C=C[C@]2(C)[C@]3([H])[C@@]([C@]([C@H]4C(O[C@H]5C6=COC=C6)=O)(O4)[C@@]5(C)CC3)(C)C(C[C@@]2([H])C(C)(C)O1)=O
InChI: 1S/C26H30O7/c1-22(2)16-12-17(27)25(5)15(23(16,3)9-7-18(28)32-22)6-10-24(4)19(14-8-11-30-13-14)31-21(29)20-26(24,25)33-20/h7-9,11,13,15-16,19-20H,6,10,12H2,1-5H3/t15-,16+,19+,20-,23-,24+,25+,26-/m1/s1
InChI key: MAYJEFRPIKEYBL-OASIGRBWSA-N
grade:
primary reference standard
product line:
phyproof® Reference Substance
Assay:
≥95.0% (HPLC)
manufacturer/tradename:
PhytoLab
format:
__
SMILES string:
O=C1C=C[C@]2(C)[C@]3([H])[C@@]([C@]([C@H]4C(O[C@H]5C6=COC=C6)=O)(O4)[C@@]5(C)CC3)(C)C(C[C@@]2([H])C(C)(C)O1)=O
InChI:
1S/C26H30O7/c1-22(2)16-12-17(27)25(5)15(23(16,3)9-7-18(28)32-22)6-10-24(4)19(14-8-11-30-13-14)31-21(29)20-26(24,25)33-20/h7-9,11,13,15-16,19-20H,6,10,12H2,1-5H3/t15-,16+,19+,20-,23-,24+,25+,26-/m1/s1
InChI key:
MAYJEFRPIKEYBL-OASIGRBWSA-N
grade: primary reference standard
product line: phyproof® Reference Substance
Assay: ≥90.0% (HPLC)
manufacturer/tradename: PhytoLab
format: neat
SMILES string: O=C1C=CC[C@](N1C2)([H])[C@@]3([H])CCC[N]4(O)CCC[C@]2([H])[C@]43[H]
InChI: 1S/C15H22N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h1,7,11-13,15H,2-6,8-10H2/t11-,12+,13+,15-,17?/m0/s1
InChI key: QMGGMESMCJCABO-LHDUFFHYSA-N
grade:
primary reference standard
product line:
phyproof® Reference Substance
Assay:
≥90.0% (HPLC)
manufacturer/tradename:
PhytoLab
format:
neat
SMILES string:
O=C1C=CC[C@](N1C2)([H])[C@@]3([H])CCC[N]4(O)CCC[C@]2([H])[C@]43[H]
InChI:
1S/C15H22N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h1,7,11-13,15H,2-6,8-10H2/t11-,12+,13+,15-,17?/m0/s1
InChI key:
QMGGMESMCJCABO-LHDUFFHYSA-N