Y0001448
Bicalutamide for system suitability
European Pharmacopoeia (EP) Reference Standard
Manufacturer: Sigma Aldrich
CAS Number: 90357-06-5
Synonym(S): Bicalutamide (CDX), Casodex, Cosudex, N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 MG | Y0001448-10-MG | In Stock | ₹ 20,794.83 |
Y0001448 - 10 MG
In Stock
Quantity
1
Base Price: ₹ 20,794.83
GST (18%): ₹ 3,743.069
Total Price: ₹ 24,537.899
grade
pharmaceutical primary standard
API family
bicalutamide
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F
InChI
1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
InChI key
LKJPYSCBVHEWIU-UHFFFAOYSA-N
Gene Information
human ... AR(367)
Other Options
Related Products
Description
- General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
- Application: Bicalutamide for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
- Biochem/physiol Actions: Bicalutamide (CDX) is a non-steriodal Androgen Receptor (AR) antagonist and a pure antiandrogen. It acts via balancing histone acetylation/deacetylation and recruitment of coregulators. Bicalutamide (CDX) abolishes androgen-mediated expression. For example, MMP13 upregulation in prostate cancer, PLZF (promyelocytic leukemia zinc finger protein), and GADD45γ (growth arrest and DNA damage inducible, gamma). Bicalutamide (CDX) is inhibited by non-genomic, transcription-independent stimulation of PI3K/AKT phosphorylation by androgens.
- Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
- Other Notes: Sales restrictions may apply.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 1 - Carc. 2 - Repr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
grade: pharmaceutical primary standard
API family: bicalutamide
manufacturer/tradename: EDQM
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F
InChI: 1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
InChI key: LKJPYSCBVHEWIU-UHFFFAOYSA-N
Gene Information: human ... AR(367)
grade:
pharmaceutical primary standard
API family:
bicalutamide
manufacturer/tradename:
EDQM
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F
InChI:
1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
InChI key:
LKJPYSCBVHEWIU-UHFFFAOYSA-N
Gene Information:
human ... AR(367)
grade: pharmaceutical primary standard
API family: chlorpromazine
manufacturer/tradename: EDQM
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: __
InChI: __
InChI key: __
Gene Information: __
grade:
pharmaceutical primary standard
API family:
chlorpromazine
manufacturer/tradename:
EDQM
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
__
InChI:
__
InChI key:
__
Gene Information:
__
grade: pharmaceutical primary standard
API family: captopril
manufacturer/tradename: EDQM
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: __
InChI: 1S/C11H17NO4S/c1-7(6-17-8(2)13)10(14)12-5-3-4-9(12)11(15)16/h7,9H,3-6H2,1-2H3,(H,15,16)/p-1/t7-,9+/m1/s1
InChI key: ZNQRGUYIKSRYCI-APPZFPTMSA-M
Gene Information: __
grade:
pharmaceutical primary standard
API family:
captopril
manufacturer/tradename:
EDQM
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
__
InChI:
1S/C11H17NO4S/c1-7(6-17-8(2)13)10(14)12-5-3-4-9(12)11(15)16/h7,9H,3-6H2,1-2H3,(H,15,16)/p-1/t7-,9+/m1/s1
InChI key:
ZNQRGUYIKSRYCI-APPZFPTMSA-M
Gene Information:
__
grade: pharmaceutical primary standard
API family: chlortetracycline
manufacturer/tradename: EDQM
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O
InChI: 1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1
InChI key: CBHYYLPALVVVEY-LYNLVHCPSA-N
Gene Information: __
grade:
pharmaceutical primary standard
API family:
chlortetracycline
manufacturer/tradename:
EDQM
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O
InChI:
1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1
InChI key:
CBHYYLPALVVVEY-LYNLVHCPSA-N
Gene Information:
__