Y0001761

Nicorandil

European Pharmacopoeia (EP) Reference Standard

Manufacturer: Sigma Aldrich

CAS Number: 65141-46-0

Synonym(S): 2-(Pyridine-3-carbonylamino)ethyl nitrate, 2-Nicotinamidoethyl nitrate, Ikorel, N-[2-(Nitrooxy)ethyl]-3-pyridinecarboxamide, SG-75, Sigmart, Zynicor

Select a Size

Pack Size SKU Availability Price
5 MG Y0001761-5-MG In Stock ₹ 14,072.50

Y0001761 - 5 MG

₹ 14,072.50

In Stock

Quantity

1

Base Price: ₹ 14,072.50

GST (18%): ₹ 2,533.05

Total Price: ₹ 16,605.55

grade

pharmaceutical primary standard

API family

nicorandil

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

[O-][N+](=O)OCCNC(=O)c1cccnc1

InChI

1S/C8H9N3O4/c12-8(7-2-1-3-9-6-7)10-4-5-15-11(13)14/h1-3,6H,4-5H2,(H,10,12)

InChI key

LBHIOVVIQHSOQN-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
50-176-4174
Sigma Aldrich Fine Chemicals Biosciences Nicorandil >=98% (HPLC) | 65141-46-0 | MFCD00186520 | 50MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 9,265.29
50-197-0108
Medchemexpress LLC HY-B0341 100mg Medchemexpress, Nicorandil CAS:65141-46-0 Purity:>98%
Medchemexpress LLC ₹ 5,480.12
50-176-4175
Sigma Aldrich Fine Chemicals Biosciences Nicorandil European Pharmacopoeia (EP) Reference Standard | 65141-46-0 | MFCD00186520 |
Sigma Aldrich Fine Chemicals Biosciences ₹ 16,036.51
BP1103
Nicorandil
Sigma Aldrich ₹ 23,944.90
CS-2383
Nicorandil
ChemScene ₹ 6,930.36
AB77483
65141-46-0 | 2-(pyridin-3-ylformamido)ethyl nitrate
A2B Chem ₹ 1,283.40 - ₹ 8,213.76

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Description

  • General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
  • Application: Nicorandil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
  • Biochem/physiol Actions: Nicorandil is a hybrid ATP-sensitive K+ (KATP) channel opener and nicotinamide nitrate NO donor. Nicorandil selectively activates SUR2B- versus SUR2A-containing KATP channels. It enhances endothelial NO synthase expression and protects against ischemic ventricular arrhythmias. By activating potassium channels, and donating nitric oxide to activate the enzyme guanylate cyclase, Nicorandil causes activation of GMP leading to both arterial and venous vasodilatation. Nicorandil is selective for vascular potassium channels, but has no significant action on cardiac contractility and conduction.
  • Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
  • Other Notes: Sales restrictions may apply.

SAFETY INFORMATION

Pictograms

GHS02,GHS07

Signal Word

Danger

Hazard Statements

H242,H302

Precautionary Statements

P210 - P235 - P280 - P301 + P312 - P370 + P378 - P410

Hazard Classifications

Acute Tox. 4 Oral - Org. Perox. D

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

Y0001761

European Pharmacopoeia (EP) Referen...


grade:
pharmaceutical primary standard

API family:
nicorandil

manufacturer/tradename:
EDQM

application(s):
pharmaceutical (small molecule)

format:
neat

storage temp.:
−20°C

SMILES string:
[O-][N+](=O)OCCNC(=O)c1cccnc1

InChI:
1S/C8H9N3O4/c12-8(7-2-1-3-9-6-7)10-4-5-15-11(13)14/h1-3,6H,4-5H2,(H,10,12)

InChI key:
LBHIOVVIQHSOQN-UHFFFAOYSA-N

Img

Sigma Aldrich

Y0001762

European Pharmacopoeia (EP) Referen...


grade:
pharmaceutical primary standard

API family:
nicorandil

manufacturer/tradename:
EDQM

application(s):
pharmaceutical (small molecule)

format:
neat

storage temp.:
−20°C

SMILES string:
__

InChI:
1S/C8H9N3O4/c12-8(7-1-3-9-4-2-7)10-5-6-15-11(13)14/h1-4H,5-6H2,(H,10,12)

InChI key:
VZCYAIHIDPPQHC-UHFFFAOYSA-N

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Y0001763

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grade:
pharmaceutical primary standard

API family:
solifenacin

manufacturer/tradename:
EDQM

application(s):
pharmaceutical (small molecule)

format:
neat

storage temp.:
2-8°C

SMILES string:
OC(CCC(O)=O)=O.O=C(O[C@H]1CN2CCC1CC2)N3[C@@H](C4=CC=CC=C4)C5=CC=CC=C5CC3

InChI:
1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21?,22-;/m0./s1

InChI key:
RXZMMZZRUPYENV-DZSUWJOWSA-N

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Sigma Aldrich

Y0001765

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grade:
pharmaceutical primary standard

API family:
atracurium, cisatracurium

manufacturer/tradename:
EDQM

application(s):
pharmaceutical (small molecule)

format:
neat

storage temp.:
__

SMILES string:
__

InChI:
1S/C21H27NO4/c1-22-9-8-15-12-20(25-4)21(26-5)13-16(15)17(22)10-14-6-7-18(23-2)19(11-14)24-3/h6-7,11-13,17H,8-10H2,1-5H3

InChI key:
KGPAYJZAMGEDIQ-UHFFFAOYSA-N