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50-112-3170

TCR beta Monoclonal Antibody (H57-597), APC, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size	SKU	Availability	Price
Each of 1	50-112-3170-Each-of-1	In Stock	₹ 40,406.00

50-112-3170 - Each of 1

₹ 40,406.00

In Stock

Quantity

Base Price: ₹ 40,406.00

GST (18%): ₹ 7,273.08

Total Price: ₹ 47,679.08

Antigen

TCR beta

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Gene Symbols

Tcrb

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21577

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

H57-597

Conjugate

APC

Gene

Tcrb

Gene Alias

bTCR; FLJ22602; MGC117436; MGC22624; MGC23964; MGC71411; T cell receptor beta chain; t-cell antigen receptor; T-cell receptor; TCR beta; Tcra; Tcrb; TCRbeta; TCRD; Tib; TRA

Host Species

Armenian Hamster

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

Description: The H57-597 monoclonal antibody reacts with the beta chain of mouse TCR
TCR beta is expressed by thymocytes in a developmentally regulated manner and a majority of peripheral T cells
Crosslinking of the TCR complex with H57-597 induces activation and proliferation of T cells or apoptosis based on assay conditions
H57-597 is used as a phenotypic marker for TCR beta expressing T cells
Applications Reported: The H57-597 antibody has been reported for use in flow cytometric analysis
Applications Tested: The H57-597 antibody has been tested by flow cytometric analysis of mouse thymocytes and splenocytes
This can be used at less than or equal to 0.125 μg per test
A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
Filtration: 0.2 μm post-manufacturing filtered
The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
TCR recognition of self-peptides has been linked to autoimmune disease
Mutant self-peptides have been associated with tumors
Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease (ref5)
T Cell and TCR Diversity Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
A small number of T cells lack both CD4 and CD8 (double negative, DN)
Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
Gamma-delta T cells are primarily found within the epithelium
They show less TCR diversity and recognize antigens differently than alpha-beta T cells
Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Compare Similar Items

Show Difference

Fischer Scientific

50-112-3170

Antigen:

TCR beta

Classification:

Monoclonal

Concentration:

0.2 mg/mL

Formulation:

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:

0

Gene Symbols:

Tcrb

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

21577

Content And Storage:

4° C, store in dark, DO NOT FREEZE!

Form:

Liquid

Applications:

Flow Cytometry

Clone:

H57-597

Conjugate:

APC

Gene:

Tcrb

Gene Alias:

bTCR; FLJ22602; MGC117436; MGC22624; MGC23964; MGC71411; T cell receptor beta chain; t-cell antigen receptor; T-cell receptor; TCR beta; Tcra; Tcrb; TCRbeta; TCRD; Tib; TRA

Host Species:

Armenian Hamster

Quantity:

200 μg

Primary or Secondary:

Primary

Target Species:

Mouse

Product Type:

Antibody

Isotype:

IgG

Fischer Scientific

50-112-3173

Antigen:

MHC Class I (H-2Kd/H-2Dd)

Classification:

Monoclonal

Concentration:

0.2 mg/mL

Formulation:

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:

P01895, P01896, P01897, P01899, P01900, P01901, P03991, P04223, P14426, P14427, P14428

Gene Symbols:

H2-D1, H2-K1

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

14964, 14972

Content And Storage:

4° C, store in dark, DO NOT FREEZE!

Form:

Liquid

Applications:

Flow Cytometry

Clone:

34-1-2S

Conjugate:

APC

Gene:

H2-D1

Gene Alias:

class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, D-B alpha chain; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2D; H2-D; H-2D cell surface glycoprotein; H-2D(B); H2-D1; H2-DC1-beta transplantation antigen protein; H2DD; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2K1; H2-K1; H2KD; histocompatibility 2, D region locus 1; histocompatibility 2, K1, K region; K-f; MHC class I antigen; MHC class I H2 antigen; MHC class I H-2Dp; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-D-q alpha-chain; MHC H2-K transplantation antigen; Q5k protein

Host Species:

Mouse

Quantity:

25 μg

Primary or Secondary:

Primary

Target Species:

Mouse

Product Type:

Antibody

Isotype:

IgG2a κ

Fischer Scientific

50-112-3174

Antigen:

MHC Class I (H-2Kd/H-2Dd)

Classification:

Monoclonal

Concentration:

0.2 mg/mL

Formulation:

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:

P01895, P01896, P01897, P01899, P01900, P01901, P03991, P04223, P14426, P14427, P14428

Gene Symbols:

H2-D1, H2-K1

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

14964, 14972

Content And Storage:

4° C, store in dark, DO NOT FREEZE!

Form:

Liquid

Applications:

Flow Cytometry

Clone:

34-1-2S

Conjugate:

APC

Gene:

H2-K1

Gene Alias:

class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, D-B alpha chain; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2D; H2-D; H-2D cell surface glycoprotein; H-2D(B); H2-D1; H2-DC1-beta transplantation antigen protein; H2DD; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2K1; H2-K1; H2KD; histocompatibility 2, D region locus 1; histocompatibility 2, K1, K region; K-f; MHC class I antigen; MHC class I H2 antigen; MHC class I H-2Dp; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-D-q alpha-chain; MHC H2-K transplantation antigen; Q5k protein

Host Species:

Mouse

Quantity:

100 μg

Primary or Secondary:

Primary

Target Species:

Mouse

Product Type:

Antibody

Isotype:

IgG2a κ

Invitrogen

50-112-3177

Antigen:

CX3CR1

Classification:

Monoclonal

Concentration:

5 μL/Test

Formulation:

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:

P49238

Gene Symbols:

CX3CR1

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

1524

Content And Storage:

4° C, store in dark, DO NOT FREEZE!

Form:

Liquid

Applications:

Flow Cytometry

Clone:

2A9-1

Conjugate:

APC

Gene:

CX3CR1

Gene Alias:

Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28

Host Species:

Rat

Quantity:

100 Tests

Primary or Secondary:

Primary

Target Species:

Human

Product Type:

Antibody

Isotype:

IgG2b κ

TCR beta Monoclonal Antibody (H57-597), APC, eBioscience™, Invitrogen™

Select a Size

Select a Size

Properties

Antigen

Classification

Concentration

Formulation

Gene Accession No.

Gene Symbols

Purification Method

Regulatory Status

Gene ID (Entrez)

Content And Storage

Form

Applications

Clone

Conjugate

Gene

Gene Alias

Host Species

Quantity

Primary or Secondary

Target Species

Product Type

Isotype

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Description

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