5386822
Murine anti-PON1, Clone: KRJ2, ZeptoMetrix
Murine Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PON1
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Immunogen
Recombinant human PON1 produced in E. coli
Primary or Secondary
Primary
Content And Storage
Store at −10°C or below. Avoid freeze/thaw cycles. Thawed material may be stored at 4°C for short-term use.
Clone
KRJ2
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Isotype
IgG1
Purification Method
Affinity Purified
Related Products
Description
- PON1 (arylesterase/paraoxonase) is a polymorphic enzyme closely associated with high-density lipoproteins (HDL)
- It is located on chromosome 7 along with 2 other paraoxanase genes, PON2 and PON3
- It is a 355 amino acid, 43kDa glycoprotein produced in the liver and secreted into the bloodstream
- Gene polymorphisms occur in both coding and non-coding regions
- Two major polymorphisms in the coding region are L55M and Q192R
- Q192R polymorphisms result in three major functional phenotypes Q/Q, Q/R and RR
- PON1 hydrolyses organophosphates and prevents the oxidation of low-density lipoproteins (LDL)
- It may inhibit the progression of atherosclerosis by inhibition of LDL oxidation
- Levels of PON1 in serum vary among individuals and are decreased in chronic renal failure, liver cirrhosis, diabetes, peripheral neuropathy, and familial hypercholesterolemia.
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Antigen: PON1
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Immunogen: Recombinant human PON1 produced in E. coli
Primary or Secondary: Primary
Content And Storage: Store at −10°C or below. Avoid freeze/thaw cycles. Thawed material may be stored at 4°C for short-term use.
Clone: KRJ2
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Isotype: IgG1
Purification Method: Affinity Purified
Antigen:
PON1
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Immunogen:
Recombinant human PON1 produced in E. coli
Primary or Secondary:
Primary
Content And Storage:
Store at −10°C or below. Avoid freeze/thaw cycles. Thawed material may be stored at 4°C for short-term use.
Clone:
KRJ2
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Isotype:
IgG1
Purification Method:
Affinity Purified
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