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ABN219125UL

Calretinin, Rabbit anti-Rat, Human, Polyclonal, Millipore Sigma™

Manufacturer: MilliporeSigma

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN219125UL-Each-of-1 In Stock ₹ 17,118.26

ABN219125UL - Each of 1

₹ 17,118.26

In Stock

Quantity

1

Base Price: ₹ 17,118.26

GST (18%): ₹ 3,081.287

Total Price: ₹ 20,199.547

Antigen

Calretinin

Classification

Polyclonal

Dilution

Western Blotting Analysis: A 1:500 dilution from a representative lot detected Calretinin in rat brain tissue lysate.Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Calretinin in human cerebral cortex and rat cerebellum tissue sections.

Gene Alias

CR

Host Species

Rabbit

Molecular Weight of Antigen

∽31 kDa observed; 31.41 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity

25 μL

Research Discipline

Neuroscience

Test Specificity

This rabbit polyclonal antibody detects Calretinin in human and rat cells. It targets an epitope within 99 amino acids from the internal region.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

Calb2

Immunogen

GST/His-tagged recombinant fragment corresponding to 99 amino acids from the internal region of rat Calretinin.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Rat, Human

Isotype

IgG

Description

  • Anti-Calretinin Antibody, Cat
  • No
  • ABN2191, is a highly specific rabbit polyclonal antibody that targets Calretinin and has been tested in Immunohistochemistry (Paraffin) and Western Blotting
  • Calretinin (UniProt: P47728; also known as CR) is encoded by the Calb2 gene (Gene ID: 117059) in rat
  • Calretinin belongs to the calbindin protein family and acts as a calcium-binding protein
  • It is expressed in both central and peripheral nervous system and is found abundantly in auditory neurons
  • It is involved in regulating cytosolic calcium ion concentrations and has multiple calcium-binding domains known as EF-hands
  • Its expression is shown to be regulated at the level of transcription by nuclear respiratory factor 1 (NRF-1) and E2F2 transcription factors
  • In rat striatum calretinin neurons form a distinct subset of medium-sized (7 20μm), aspiny, GABAergic interneurons
  • Calretinin can also serve as an important differential diagnostic tool for cystic and solid ameloblastic tumors
  • (Ref.: Petryszyn, S., et al
  • (2017)
  • J
  • Neural Transm
  • doi: 10.1007/s00702-017-1687; Kresoja-Rakic, J., et al
  • (2017)
  • Front
  • Genet
  • doi: 10.3389/fgene.2017.00070).