AMPA6570

FANCD2 Monoclonal Antibody (FI-17), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 AMPA6570-Each-of-1 In Stock ₹ 45,817.38

AMPA6570 - Each of 1

₹ 45,817.38

In Stock

Quantity

1

Base Price: ₹ 45,817.38

GST (18%): ₹ 8,247.128

Total Price: ₹ 54,064.508

Antigen

FANCD2

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.1% sodium azide

Gene Accession No.

Q9BXW9

Gene Symbols

FANCD2

Immunogen

FANCD2 fusion protein

Regulatory Status

RUO

Gene ID (Entrez)

2177

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

FI-17

Conjugate

Unconjugated

Gene

FANCD2

Gene Alias

2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • By Western blot, this antibody recognizes a band at ∽155 and ∽162 kDa (post-translationally modified form)
  • Suggested positive control: Hela whole cell extract
  • FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability
  • It promotes accurate and efficient pairing of homologs during meiosis
  • FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing
  • It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress
  • FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin
  • Defects in the FANCD2 gene result in Fanconi anemia complementation group D2
  • This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.

Compare Similar Items

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Img

Thermo Scientific

AMPA6570

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Antigen:
FANCD2

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.1% sodium azide

Gene Accession No.:
Q9BXW9

Gene Symbols:
FANCD2

Immunogen:
FANCD2 fusion protein

Regulatory Status:
RUO

Gene ID (Entrez):
2177

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
FI-17

Conjugate:
Unconjugated

Gene:
FANCD2

Gene Alias:
2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

AMPA6573

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Antigen:
Separase

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.1% sodium azide

Gene Accession No.:
P60330, Q14674

Gene Symbols:
ESPL1

Immunogen:
Maltose-Binding Protein fusion of the C-terminal residues 1866-1996 of human separase.

Regulatory Status:
RUO

Gene ID (Entrez):
105988, 9700

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
XJ11-4D7

Conjugate:
Unconjugated

Gene:
ESPL1

Gene Alias:
AL024103; AU045071; Caspase-like protein ESPL1; Cerp; Cut1/ESP1 related protein; ESP1; ESPL1; extra spindle pole bodies 1 (S. cerevisiae); extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle pole bodies homolog 1 (S. cerevisiae); extra spindle pole bodies like 1, separase; extra spindle poles like 1; extra spindle poles-like 1 protein; FLJ46492; KIAA0165; PRCE; SEPA; separase; Separin; separin, cysteine protease; SSE

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

AMPA6578

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Antigen:
RPE65

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O70276, Q16518, Q28175, Q91ZQ5, Q9TVB8, Q9YGX2

Gene Symbols:
RPE65

Immunogen:
Bovine RPE65 microsomal membrane proteins.

Regulatory Status:
RUO

Gene ID (Entrez):
100516743, 19892, 282043, 395700, 403803, 6121, 89826

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
401.8B11.3D9

Conjugate:
Unconjugated

Gene:
RPE65

Gene Alias:
65kDa; A930029L06Rik; all-trans-retinyl-palmitate hydrolase; BCO family, member 3; BCO3; LCA2; Lutein isomerase; membrane receptor p63; meso-zeaxanthin isomerase; modifier of retinal degeneration 1; Mord1; mRPE65; p63; RBP-binding membrane protein; rd12; retinal pigment epithelium 65; retinal pigment epithelium 65-like; retinal pigment epithelium abundant protein RPE65; retinal pigment epithelium specific protein 65; retinal pigment epithelium, 65 kDa; retinal pigment epithelium-specific 65 kDa protein; retinal pigment epithelium-specific 65kD protein; retinal pigment epithelium-specific protein (65kD); retinal pigment epithelium-specific protein 65kDa; retinal pigment epithelium-specific protein RPE65; Retinitis pigmentos; retinitis pigmentosa 20 (autosomal recessive); retinoid isomerohydrolase; retinoid isomerohydrolase RPE65; retinol isomerase; RP20; RPE65; rpe65 gene for retinal pigment epithelium-specific protein; RPE65, retinoid isomerohydrolase; sRPE65; truncated RPE65

Host Species:
Mouse

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Chicken, Human, Mouse, Non-human Primate, Porcine, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Thermo Scientific

AMPA6587

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Antigen:
14-3-3 gamma

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P61981

Gene Symbols:
YWHAG

Immunogen:
N-terminal fragment of human 14-3-3 gamma where the N-terminal Val was acetylated.

Regulatory Status:
RUO

Gene ID (Entrez):
7532

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
KC21

Conjugate:
Unconjugated

Gene:
YWHAG

Gene Alias:
14-3-3 gamma; 14-3-3 protein gamma; 14-3-3 protein gamma subtype; 14-3-3 protein gamma, N-terminally processed; 14-3-3 protein gamma-1; 14-3-3 protein gamma-subtype; 14-3-3G; 14-3-3gamma; 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide; 3-monooxgenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 3-monooxygenase/tryptophan 5-monooxgenase activation protein gamma polypeptide; 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; cb47; D7Bwg1348e; fd20c02; hypothetical protein; KCIP-1; PPP1R170; Protein kinase C inhibitor protein 1; protein phosphatase 1, regulatory subunit 170; RCJMB04_5e12; tryosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein gamma; tryosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein gamma polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein gamma polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, gamma polypeptide; tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; wu:fd20c02; wu:fj53d01; ywhag; ywhag1; zgc:73131

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a