PIMA1218

HP1 alpha Monoclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA1218-Each-of-1 In Stock ₹ 49,325.34

PIMA1218 - Each of 1

₹ 49,325.34

In Stock

Quantity

1

Base Price: ₹ 49,325.34

GST (18%): ₹ 8,878.561

Total Price: ₹ 58,203.901

Antigen

HP1 alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide; pH 7.2-7.4

Gene Accession No.

P45973

Gene Symbols

Cbx5

Immunogen

Purified recombinant fragment of human CBX5 (AA: 1-191) expressed in E. Coli

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

Monoclonal

Conjugate

Unconjugated

Gene

Cbx5

Gene Alias

2610029O15Rik, antigen p25, C75991, Cbx5, Cbx5 antibody, chromobox 5, chromobox homolog 5, chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, chromobox-like protein 5, epididymis luminal protein 25, HEL25, heterochromatin protein 1 alpha, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha, HGNC:1555, HP1, HP1 alpha, HP-1 alpha antibody, HP1 alpha homolog, Hp1a, Hp1alpha, HP1-ALPHA, HP1Hs alpha, HP1Hs-alpha, mHP1(alpha)

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

23468

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Novus Biologicals

NBP252434

--

Img

Novus Biologicals

NB11040623

--

Img

Novus Biologicals

NBP259154

--

Img

Thermo Scientific

PIPA531078

--

Img

Thermo Scientific

PIPA5110811

--

Img

Thermo Scientific

PIPA554007

--

Img

Thermo Scientific

PIPA531113

--

Img

Novus Biologicals

NB163375

--

Description

  • MA1-218 detects CBX5 from human and non-human primate samples
  • CBX5 has an approximate molecular weight of 22.2kDa
  • MA1-218 has been successfully used in Western blot, immunofluorescence,and immunohistochemistry applications
  • The MA1-218 Immunogen is the purified recombinant fragment of human CBX5 (AA: 1-191) expressed in E
  • Coli
  • Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing
  • It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure
  • High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain
  • Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3
  • In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mouse fibroblasts but is restored after reintroduction of a catalytically active SUV39H1 HMTase.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA1218

--


Antigen:
HP1 alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide; pH 7.2-7.4

Gene Accession No.:
P45973

Gene Symbols:
Cbx5

Immunogen:
Purified recombinant fragment of human CBX5 (AA: 1-191) expressed in E. Coli

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
Monoclonal

Conjugate:
Unconjugated

Gene:
Cbx5

Gene Alias:
2610029O15Rik, antigen p25, C75991, Cbx5, Cbx5 antibody, chromobox 5, chromobox homolog 5, chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, chromobox-like protein 5, epididymis luminal protein 25, HEL25, heterochromatin protein 1 alpha, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha, HGNC:1555, HP1, HP1 alpha, HP-1 alpha antibody, HP1 alpha homolog, Hp1a, Hp1alpha, HP1-ALPHA, HP1Hs alpha, HP1Hs-alpha, mHP1(alpha)

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23468

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA1219

--


Antigen:
Prom1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O43490

Gene Symbols:
PROM1

Immunogen:
Purified recombinant fragment of human Prom1 (AA:20-108) expressed in E.Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot

Clone:
2F8C5

Conjugate:
Unconjugated

Gene:
PROM1

Gene Alias:
4932416E19Rik, AC133, Antigen AC133, antigen AC133 homolog, antigen CD133, CD107b, CD133, CORD12, fudenine, hematopoietic stem cell antigen, hProminin, Lamp II, Lamp2, LAMP-2, Lamp-2a, Lamp-2b, Lamp-2c, LGP-96, LGP-B, Mac3, MCDR2, MSTP061, Prom, PROM1, Prom-1, prominin 1, prominin 1.s1, Prominin1, prominin-1, prominin-1.s2, prominin-like 1, prominin-like protein 1, PROML1, RP41, STGD4

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8842

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA122009

--


Antigen:
Blooms Syndrome

Classification:
Monoclonal

Concentration:
0.7 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P54132

Gene Symbols:
BLM

Immunogen:
Recombinant full length protein (Human).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Frozen), Western Blot

Clone:
BFL-103

Conjugate:
Unconjugated

Gene:
BLM

Gene Alias:
Blm; Bloom syndrome homolog; Bloom syndrome protein; Bloom syndrome protein homolog; Bloom syndrome RecQ like helicase; Bloom syndrome, RecQ helicase-like; BS; DNA helicase, RecQ-like type 2; mBLM; MGC126616; MGC131618; MGC131620; RecQ helicase homolog; recQ protein-like 3; RecQ2; RECQL2; RECQL3

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
641

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA122084

--


Antigen:
Leptin

Classification:
Monoclonal

Concentration:
5.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P41159

Gene Symbols:
Lep

Immunogen:
Recombinant full length protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
4F12

Conjugate:
Unconjugated

Gene:
Lep

Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3952

Content And Storage:
4° C

Form:
Liquid