Myeloperoxidase (MPO) Rabbit Polyclonal Antibody, Epredia™

Description

• Myeloperoxidase is an important enzyme used by granulocytes during phagocytic lysis of foreign particles engulfed
• In normal tissues and in a variety of myeloproliferative disorders myeloid cells of both neutrophilic and eosinophilic types, at all stages of maturation, exhibit strong cytoplasmic reactivity for MPO
• Erythroid precursors, megakaryocytes, lymphoid cells, mast cells, and plasma cells are nonreactive
• MPO is not observed in the neoplastic cells of a wide variety of epithelial tumors and sarcomas
• MPO is useful in differentiating between myeloid and lymphoid leukemias
• Host Species: Rabbit Isotype: IgG Species Reactivity: Human, Mouse and Rat
• Others not known
• Epitope: Not determined Immunogen: Purified human granulocytic MPO Positive Control: Tonsil or spleen Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)