1711202

Verapamil hydrochloride

United States Pharmacopeia (USP) Reference Standard

Manufacturer: Sigma Aldrich

CAS Number: 152-11-4

Synonym(S): (±)-Verapamil hydrochloride, 5-[N-(3,4-Dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochloride

Select a Size

Pack Size SKU Availability Price
200 MG 1711202-200-MG In Stock ₹ 46,222.75

1711202 - 200 MG

₹ 46,222.75

In Stock

Quantity

1

Base Price: ₹ 46,222.75

GST (18%): ₹ 8,320.095

Total Price: ₹ 54,542.845

grade

pharmaceutical primary standard

API family

verapamil

manufacturer/tradename

USP

mp

142 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC

InChI

1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H

InChI key

DOQPXTMNIUCOSY-UHFFFAOYSA-N

Gene Information

human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)

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Description

  • General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
  • Application: Verapamil hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
  • Biochem/physiol Actions: α1-adrenoceptor antagonist; L-type calcium channel blocker. Blocks L-type Ca2+ channels in smooth and cardiac muscle, induces apoptosis of human primary and metastatic colon adenocarcinoma cells in vitro. Drug resistance reversal agent acting on Pgp, e.g. decrease renal tubule elimination of digoxin. Increases basal ATPase activity of Pgp. Substrate of Cyp3A4 and CYP2C6.
  • Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
  • Other Notes: Sales restrictions may apply.

SAFETY INFORMATION

Pictograms

GHS06,GHS09

Signal Word

Danger

Hazard Statements

H301,H411

Precautionary Statements

P264 - P273 - P301 + P310 - P391 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Show Difference

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Sigma Aldrich

1711202

United States Pharmacopeia (USP) Re...


grade:
pharmaceutical primary standard

API family:
verapamil

manufacturer/tradename:
USP

mp:
142 °C (dec.) (lit.)

application(s):
pharmaceutical (small molecule)

format:
neat

SMILES string:
Cl.COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC

InChI:
1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H

InChI key:
DOQPXTMNIUCOSY-UHFFFAOYSA-N

Gene Information:
human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)

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Sigma Aldrich

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venlafaxine

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mp:
__

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format:
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SMILES string:
__

InChI:
1S/C16H25NO2.ClH/c1-17-12-15(16(18)10-4-3-5-11-16)13-6-8-14(19-2)9-7-13;/h6-9,15,17-18H,3-5,10-12H2,1-2H3;1H

InChI key:
HWPAFKGYJZARRM-UHFFFAOYSA-N

Gene Information:
__

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grade:
pharmaceutical primary standard

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mp:
__

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format:
neat

SMILES string:
__

InChI:
1S/C17H26N2O2.ClH/c1-13(2)17(12-18,9-6-10-19-3)14-7-8-15(20-4)16(11-14)21-5;/h7-8,11,13,19H,6,9-10H2,1-5H3;1H

InChI key:
ARLOHZJIIHSRFE-UHFFFAOYSA-N

Gene Information:
__

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grade:
pharmaceutical primary standard

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verapamil

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pharmaceutical (small molecule)

format:
neat

SMILES string:
__

InChI:
1S/C26H36N2O4.ClH/c1-19(2)26(18-27,21-9-11-23(30-5)25(17-21)32-7)13-15-28(3)14-12-20-8-10-22(29-4)24(16-20)31-6;/h8-11,16-17,19H,12-15H2,1-7H3;1H

InChI key:
FVLOHGQKBZSXNK-UHFFFAOYSA-N

Gene Information:
__