39220

Dansyl chloride

suitable for fluorescence, BioReagent, ≥99.0% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 605-65-2

Synonym(S): 1-Dimethylaminonaphthalene-5-sulfonyl chloride, 5-(Dimethylamino) naphthalene-1-sulfonyl chloride, DNS Chloride, DNSCl, 5-(Dimethylamino)naphthalene-1-sulfonyl chloride

Select a Size

Pack Size SKU Availability Price
1 G 39220-1-G In Stock ₹ 13,531.25
5 G 39220-5-G In Stock ₹ 67,418.10
50 G 39220-50-G In Stock ₹ 2,62,874.30

39220 - 1 G

₹ 13,531.25

In Stock

Quantity

1

Base Price: ₹ 13,531.25

GST (18%): ₹ 2,435.625

Total Price: ₹ 15,966.875

product line

BioReagent

Quality Level

200

Assay

≥99.0% (HPLC)

mp

72-74 °C (lit.)

solubility

acetone: 0.2 g/10 mL

fluorescence

λex 337 nm; λem 492 nm in chloroform (after derivatization with hexylamine)

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O

InChI

1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3

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Description

  • General description: Dansyl Chloride, also known as 5-dimethylamino naphthalene-1-sulfonyl chloride, is a pre-column derivatization reagent. [1] After the derivatization reaction, the fluorescent derivatives are analyzed using several analytical methods like NMR, IR, UV-vis, and fluorescence microscopy.[2] Dansyl Chloride is a typical aromatic sulphonyl chloride that reacts with various bases, resulting in derivatives with variable stability.
  • Application: Dansyl Chloride is used as a derivatization reagent to study extensive metabolism and low doses of ethinylestradiol administered during pre-clinical studies.[3] Studies conducted to determine bisphenols in human serum through the HPLC method used Dansyl Chloride to obtain the derivative products.[4] Dansyl Chloride derivatives are suitable for LC/MS determination and characterization of glyphosate, aminomethylphosphonic acid (AMPA), and glufosinate from food samples.[1]

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Danger

Hazard Statements

H290,H314

Precautionary Statements

P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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suitable for fluorescence, BioReage...


product line:
BioReagent

Quality Level:
200

Assay:
≥99.0% (HPLC)

mp:
72-74 °C (lit.)

solubility:
acetone: 0.2 g/10 mL

fluorescence:
λex 337 nm; λem 492 nm in chloroform (after derivatization with hexylamine)

suitability:
suitable for fluorescence

storage temp.:
2-8°C

SMILES string:
CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O

InChI:
1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3

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[Ce+3].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O

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1S/Ce.3NO3.6H2O/c;3*2-1(3)4;;;;;;/h;;;;6*1H2/q+3;3*-1;;;;;;

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[Ce+3].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O

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SMILES string:
OC(=O)[C@@H]1CNC(=O)N1C(=O)OCc2ccccc2

InChI:
1S/C12H12N2O5/c15-10(16)9-6-13-11(17)14(9)12(18)19-7-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,17)(H,15,16)/t9-/m0/s1