61-545
Tocris Bioscience™ MZ 1
Manufacturer: Tocris Bioscience™
CAS Number: 1797406-69-9
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 61-545-Each-of-1 | In Stock | ₹ 47,348.00 |
61-545 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,348.00
GST (18%): ₹ 8,522.64
Total Price: ₹ 55,870.64
Product Type
Cell Degrader
CAS
1797406-69-9
Formula Weight
1002.64g/mol
For Use With (Application)
Bromodomain Inhibitors
Target Proteins
Bromodomain
Molecular Formula
C49H60ClN9O8S2
Content And Storage
Store at -20°C
Quantity
5 mg
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | MZ 1 | ChemScene | ₹ 10,858.00 - ₹ 1,37,416.00 | |
 | 1797406-69-9 | MZ1 | A2B Chem | ₹ 2,047.00 - ₹ 1,53,080.00 |
Related Products
Description
- Cell penetrant Degrader (PROTAC®) compound based on (+)-JQ1 (Cat.No
- 4499) conjugated to a von Hippel-Lindau (VHL) ligand
- MZ 1 retains high affinity for BRD2, BRD3 and BRD4 bromodomains (Kd = 13-60 nM) but induces preferential degradation of BRD4 over BRD2 and BRD3 (DC50 values for degradation of BRD4 are 8 and 23 nM in H661 and H838 cells, respectively)
- Exhibits potent cytotoxicity and antiproliferative effects in AML cell lines (pEC50 = 7.6 in Mv4-11 cells)
- Negative control cis MZ 1 also available
- PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Compare Similar Items
Show Difference
Product Type: Cell Degrader
CAS: 1797406-69-9
Formula Weight: 1002.64g/mol
For Use With (Application): Bromodomain Inhibitors
Target Proteins: Bromodomain
Molecular Formula: C49H60ClN9O8S2
Content And Storage: Store at -20°C
Quantity: 5 mg
Product Type:
Cell Degrader
CAS:
1797406-69-9
Formula Weight:
1002.64g/mol
For Use With (Application):
Bromodomain Inhibitors
Target Proteins:
Bromodomain
Molecular Formula:
C49H60ClN9O8S2
Content And Storage:
Store at -20°C
Quantity:
5 mg
Product Type: PROTAC Controls
CAS: 1797406-72-4
Formula Weight: 1002.64g/mol
For Use With (Application): Bromodomain Inhibitors
Target Proteins: Bromodomain
Molecular Formula: C49H60ClN9O8S2
Content And Storage: Store at -20°C
Quantity: 5 mg
Product Type:
PROTAC Controls
CAS:
1797406-72-4
Formula Weight:
1002.64g/mol
For Use With (Application):
Bromodomain Inhibitors
Target Proteins:
Bromodomain
Molecular Formula:
C49H60ClN9O8S2
Content And Storage:
Store at -20°C
Quantity:
5 mg
Product Type: Inhibitor
CAS: __
Formula Weight: 523.65g/mol
For Use With (Application): Ubiquitin Ligase (E3) Inhibitors
Target Proteins: Ubiquitin Ligase (E3)
Molecular Formula: C27H33N5O4S
Content And Storage: Store at -20°C
Quantity: 10 mg
Product Type:
Inhibitor
CAS:
__
Formula Weight:
523.65g/mol
For Use With (Application):
Ubiquitin Ligase (E3) Inhibitors
Target Proteins:
Ubiquitin Ligase (E3)
Molecular Formula:
C27H33N5O4S
Content And Storage:
Store at -20°C
Quantity:
10 mg
Product Type: Inhibitor
CAS: __
Formula Weight: 523.65g/mol
For Use With (Application): Ubiquitin Ligase (E3) Inhibitors
Target Proteins: Ubiquitin Ligase (E3)
Molecular Formula: C27H33N5O4S
Content And Storage: Store at -20°C
Quantity: 50 mg
Product Type:
Inhibitor
CAS:
__
Formula Weight:
523.65g/mol
For Use With (Application):
Ubiquitin Ligase (E3) Inhibitors
Target Proteins:
Ubiquitin Ligase (E3)
Molecular Formula:
C27H33N5O4S
Content And Storage:
Store at -20°C
Quantity:
50 mg