62320

(±)-α-Lipoic acid

≥98.0%

Manufacturer: Sigma Aldrich

CAS Number: 1077-28-7

Synonym(S): (±)-1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL-α-Lipoic acid, DL-6,8-Thioctic acid, Lip(S2)

Select a Size

Pack Size SKU Availability Price
5 G 62320-5-G In Stock ₹ 7,599.15
25 G 62320-25-G In Stock ₹ 12,437.93

62320 - 5 G

₹ 7,599.15

In Stock

Quantity

1

Base Price: ₹ 7,599.15

GST (18%): ₹ 1,367.847

Total Price: ₹ 8,966.997

Quality Level

200

Assay

≥98.0% (HPLC)≥98.0%

form

solid

ign. residue

≤0.1%

loss

≤0.2% loss on drying

mp

60-62 °C

storage temp.

2-8°C

SMILES string

OC(=O)CCCCC1CCSS1

InChI

1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)

InChI key

AGBQKNBQESQNJD-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
PHR2561
Alpha Lipoic Acid
Supelco ₹ 17,633.93
Y0000546
Thioctic acid
Sigma Aldrich ₹ 20,567.50
Y0000545
Thioctic acid containing impurity B
Sigma Aldrich ₹ 20,567.50
Y0000592
Thioctic acid for system suitability
Sigma Aldrich ₹ 16,107.60

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Description

  • General description: α-lipoic acid (ALA, thioctic acid) is a natural organosulfur compound produced in plants, animals and humans. It is a powerful antioxidant and plays a role in the forming nucleic acids, building blocks of DNA.[1] This product is a racemic mixture.
  • Application: (±)-α-Lipoic acid has been used: In in vitro lipoylation studies and in the pyruvate dehydrogenase complex (PDC)-pyruvate dehydrogenase kinase (PDHK) functional assay.[2] To investigate its antioxidative effect on developing cerebellum of rats exposed to arsenic during postnatal period.[3]
  • Biochem/physiol Actions: (±)-α-Lipoic acid exhibits direct free radical scavenging property[4] and reduces the increased oxidative stress.[5] In addition, it might also exhibit prooxidant activity.[4] α-Lipoic acid functions as an important prosthetic group in α-keto acid dehydrogenase complexes of the mitochondria.[6] It acts as a potential therapeutic for diabetic patients with distal symmetric polyneuropathy (DSP).[5] α-Lipoic acid is also used in the treatment of energy-impaired and redox unbalanced diseases.[6]

SAFETY INFORMATION

Pictograms

GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302,H315,H317,H319,H411

Precautionary Statements

P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Assay:
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form:
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ign. residue:
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loss:
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60-62 °C

storage temp.:
2-8°C

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OC(=O)CCCCC1CCSS1

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1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)

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AGBQKNBQESQNJD-UHFFFAOYSA-N

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SMILES string:
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InChI:
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InChI key:
__