8.51009
PyBOP®
Novabiochem®
Manufacturer: Sigma Aldrich
CAS Number: 128625-52-5
Synonym(S): Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate, PyBOP®
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 G | 8.51009-25-G | In Stock | ₹ 12,010.00 |
| 100 G | 8.51009-100-G | In Stock | ₹ 35,989.99 |
| 8510091000 | 8.51009-8510091000 | In Stock | ₹ 1,73,880.00 |
8.51009 - 25 G
In Stock
Quantity
1
Base Price: ₹ 12,010.00
GST (18%): ₹ 2,161.80
Total Price: ₹ 14,171.80
Quality Level
400
product line
Novabiochem®
Assay
≥99.0% (HPLC)
form
powder
reaction suitability
reaction type: Coupling Reactions
manufacturer/tradename
Novabiochem®
greener alternative product characteristics
Less Hazardous Chemical SynthesesLearn more about the Principles of Green Chemistry.
mp
140-155 °C
application(s)
peptide synthesis
greener alternative category
Aligned
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate | Sigma Aldrich | ₹ 1,732.00 - ₹ 4,210.93 |
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Description
- General description: The standard in situ coupling reagent for solid phase peptide synthesis [1,2,3,4,5]. This product can replace BOP in all applications without loss of performance. Unlike uronium-based reagents, PyBOP® does not give rise to guanidinated by-products during cyclization and fragment condensation reactions.Associated Protocols and Technical ArticlesGuide to Selection of Coupling Reagents Literature references [1] J. Martinez, et al. (1985) J. Med. Chem., 28, 1874.[2] J. Coste, et al. (1990) Tetrahedron Lett., 31, 205.[3] G. B. Fields, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 241.[4] T. Høeg-Jensen, et al. (1991) Tetrahedron Lett., 32, 7617.[5] R. von Eggelkraut-Gottanka, et al. (2003) Tetrahedron Lett., 44, 3551.
- Linkage: Replaces: 01-62-0016
- Analysis Note: Colour (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testAssay (HPLC, area%): ≥ 99.0 % (a/a)Solubility (1 mmole in 2 ml DMF): clearly soluble
- Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Show Difference
Quality Level: 400
product line: Novabiochem®
Assay: ≥99.0% (HPLC)
form: powder
reaction suitability: reaction type: Coupling Reactions
manufacturer/tradename: Novabiochem®
greener alternative product characteristics: Less Hazardous Chemical SynthesesLearn more about the Principles of Green Chemistry.
mp: 140-155 °C
application(s): peptide synthesis
greener alternative category: Aligned
Quality Level:
400
product line:
Novabiochem®
Assay:
≥99.0% (HPLC)
form:
powder
reaction suitability:
reaction type: Coupling Reactions
manufacturer/tradename:
Novabiochem®
greener alternative product characteristics:
Less Hazardous Chemical SynthesesLearn more about the Principles of Green Chemistry.
mp:
140-155 °C
application(s):
peptide synthesis
greener alternative category:
Aligned
Quality Level: 200
product line: Novabiochem®
Assay: ≥98.0% (HPLC)
form: powder
reaction suitability: reaction type: Coupling Reactions
manufacturer/tradename: Novabiochem®
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application(s): peptide synthesis
greener alternative category: __
Quality Level:
200
product line:
Novabiochem®
Assay:
≥98.0% (HPLC)
form:
powder
reaction suitability:
reaction type: Coupling Reactions
manufacturer/tradename:
Novabiochem®
greener alternative product characteristics:
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mp:
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application(s):
peptide synthesis
greener alternative category:
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Quality Level: 300
product line: Novabiochem®
Assay: ≥98% (HPLC)
form: powder
reaction suitability: reaction type: Coupling Reactions
manufacturer/tradename: Novabiochem®
greener alternative product characteristics: __
mp: >185 °C
application(s): peptide synthesis
greener alternative category: __
Quality Level:
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product line:
Novabiochem®
Assay:
≥98% (HPLC)
form:
powder
reaction suitability:
reaction type: Coupling Reactions
manufacturer/tradename:
Novabiochem®
greener alternative product characteristics:
__
mp:
>185 °C
application(s):
peptide synthesis
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300
product line:
Novabiochem®
Assay:
__
form:
solid
reaction suitability:
reaction type: Coupling Reactions
manufacturer/tradename:
Novabiochem®
greener alternative product characteristics:
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mp:
186 °C (decomposes)
application(s):
peptide synthesis
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