Description

• General description: Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol.[1] It is found at high levels in the membranes of all cells and at low levels in fat stores.[2] 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.[3]
• Application: 18:1 (Δ9-Cis) PG has been used:in the preparation of giant unilamellar vesicle (GUV)[4]in the preparation 200 nm large unilamellar vesicles (LUV)[5]as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge[6]
• Biochem/physiol Actions: Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.[2]
• Packaging: 5 mL Clear Glass Sealed Ampule (840475P-200mg)