C2773

Cholesterol 5α,6α-epoxide

Manufacturer: Sigma Aldrich

CAS Number: 1250-95-9

Synonym(S): 5α,6α-Epoxycholestan-3β-ol

Select a Size

Pack Size SKU Availability Price
50 MG C2773-50-MG In Stock ₹ 7,750.70

C2773 - 50 MG

₹ 7,750.70

In Stock

Quantity

1

Base Price: ₹ 7,750.70

GST (18%): ₹ 1,395.126

Total Price: ₹ 9,145.826

Assay

≥80%

Quality Level

100

form

powder

functional group

epoxy

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@@]3(O4)[C@@H]4C2)([H])CC[C@@]5(C)[C@@]1([H])CC[C@]5([H])[C@]([H])(C)CCCC(C)C

InChI

1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24+,25-,26-,27+/m1/s1

InChI key

PRYIJAGAEJZDBO-ZEQHCUNVSA-N

Other Options

Image Product Name Manufacturer Price Range
50-179-6203
Sigma Aldrich Fine Chemicals Biosciences Cholesterol 5alpha,6alpha-epoxide | 1250-95-9 | MFCD00046980 | 50MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 11,319.59
CS-0136120
Cholesterol 5α,6α-epoxide
ChemScene ₹ 5,989.20
AA29574
1250-95-9 | (4aR,5aS,6aS,6bS,9R,9aR,11aS,11bR)-9a,11b-dimethyl-9-((R)-6-methylheptan-2-yl)hexadecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxiren-3-ol
A2B Chem ₹ 2,909.04 - ₹ 23,186.76

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Description

  • Application: Cholesterol 5α, 6α-epoxide was incorporated in culture medium of human arterial endothelial cells to study oxysterol-induced toxicity.[1]
  • Biochem/physiol Actions: Cholesterol 5α, 6α-epoxide is an oxysterol, a cholesterol derivative by auto-oxidation. Oxysterols are non-genomic regulators of cholesterol homeostasis.[2] The biological effects include protein prenylation, apoptosis, modulation of sphingolipid metabolism and platelet aggregation.[3] Oxysterols bind to liver X receptors, modulate cholesterol efflux and decrease the uptake of cholesterol by the cells.[2]
  • Preparation Note: Cholesterol 5α, 6α-epoxide yields clear, colorless solution in chloroform at 50 mg/ml.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@@]3(O4)[C@@H]4C2)([H])CC[C@@]5(C)[C@@]1([H])CC[C@]5([H])[C@]([H])(C)CCCC(C)C

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1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24+,25-,26-,27+/m1/s1

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PRYIJAGAEJZDBO-ZEQHCUNVSA-N

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[F-].FB(F)F.CN(C)c1cc[n+](cc1)C#N

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1S/C8H10N3.BF3.FH/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3)4;/h3-6H,1-2H3;;1H/q+1;;/p-1

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ONCRRSYBEJHQMM-UHFFFAOYSA-M

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O.O.O.O.[Ca++].[O-][N+]([O-])=O.[O-][N+]([O-])=O

InChI:
1S/Ca.2NO3.4H2O/c;2*2-1(3)4;;;;/h;;;4*1H2/q+2;2*-1;;;;

InChI key:
ICSSIKVYVJQJND-UHFFFAOYSA-N