Description

• General description: Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Baclofen is a structural analog of γ-aminobutyric acid (GABA) and an antispastic agent commonly used for the treatment of spasticity as a result of spinal cord or brain injury.[1]
• Application: Baclofen may be used as a pharmaceutical secondary reference standard for the determination of the analyte in plasma samples by liquid chromatography tandem mass spectrometry[1] and tablet formulations by UV spectroscopy,[2] respectively.
• Biochem/physiol Actions: GABAB receptor agonist; skeletal muscle relaxant; antispastic agent.
• Analysis Note: These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
• Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
• Footnote: To see an example of a Certificate of Analysis for this material enter LRAA6298 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
• Recommended products: Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.