U4375
Uridine 5′-diphospho-N-acetylglucosamine sodium salt
≥98%
Manufacturer: Sigma Aldrich
CAS Number: 91183-98-1
Synonym(S): UDP-GlcNAc, UDP-N-acetylglucosamine, UDPAG
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 MG | U4375-25-MG | In Stock | ₹ 8,220.00 |
| 100 MG | U4375-100-MG | In Stock | ₹ 24,507.80 |
| 500 MG | U4375-500-MG | In Stock | ₹ 81,458.13 |
| 1 G | U4375-1-G | In Stock | ₹ 1,46,613.80 |
U4375 - 25 MG
In Stock
Quantity
1
Base Price: ₹ 8,220.00
GST (18%): ₹ 1,479.60
Total Price: ₹ 9,699.60
biological source
bakers yeast
Quality Level
200
Assay
≥98%
form
powder
storage temp.
−20°C
SMILES string
[Na+].[Na+].CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O
InChI
1S/C17H27N3O17P2.2Na/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28;;/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28);;/q;2*+1/p-2/t7-,8-,10-,11-,12-,13-,14-,15-,16-;;/m1../s1
InChI key
HXWKMJZFIJNGES-YZVFIFBQSA-L
Other Options
Description
- General description: Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP).[1] UDP-GlcNAc is transported actively into Golgi, nucleotide sugar transporter (NST).[2] The levels of UDP-GlcNAc is modulated by the concentration of nutrients exposed to the cell.[3]
- Application: Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) sodium salt has been used: as a component of reaction cocktail in endoplasmic reticulum to Golgi transport assay[4] as a reference standard for the quantification of UDP-GlcNAc in liver tissues using high-performance liquid chromatography (HPLC)[5] in testing the glycosylation activity of O-GlcNAc transferase (OGT) against peptide substrate[6]
- Biochem/physiol Actions: Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a sugar donor and aids in the endomembrane glycosylation of endoplasmic reticulum and Golgi. The decreased levels of UDP-GlcNAc has an influence on the normal cellular proliferation and apoptosis.[1] UDP-GlcNAc elicits feedback inhibition of the enzyme glutamine:fructose-6-phosphate amidotransferase (GFAT).[3]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: bakers yeast
Quality Level: 200
Assay: ≥98%
form: powder
storage temp.: −20°C
SMILES string: [Na+].[Na+].CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O
InChI: 1S/C17H27N3O17P2.2Na/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28;;/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28);;/q;2*+1/p-2/t7-,8-,10-,11-,12-,13-,14-,15-,16-;;/m1../s1
InChI key: HXWKMJZFIJNGES-YZVFIFBQSA-L
biological source:
bakers yeast
Quality Level:
200
Assay:
≥98%
form:
powder
storage temp.:
−20°C
SMILES string:
[Na+].[Na+].CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O
InChI:
1S/C17H27N3O17P2.2Na/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28;;/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28);;/q;2*+1/p-2/t7-,8-,10-,11-,12-,13-,14-,15-,16-;;/m1../s1
InChI key:
HXWKMJZFIJNGES-YZVFIFBQSA-L
biological source: bovine milkrabbit muscleyeast
Quality Level: 200
Assay: ≥97.0%
form: powder
storage temp.: −20°C
SMILES string: [Na+].[Na+].OC[C@H]1O[C@@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@H]1O
InChI: 1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8+,9-,10+,11-,12-,13?,14?;;/m1../s1
InChI key: PKJQEQVCYGYYMM-OUJOOSCPSA-L
biological source:
bovine milkrabbit muscleyeast
Quality Level:
200
Assay:
≥97.0%
form:
powder
storage temp.:
−20°C
SMILES string:
[Na+].[Na+].OC[C@H]1O[C@@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@H]1O
InChI:
1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8+,9-,10+,11-,12-,13?,14?;;/m1../s1
InChI key:
PKJQEQVCYGYYMM-OUJOOSCPSA-L
biological source: Saccharomyces cerevisiae
Quality Level: 300
Assay: ≥98%
form: powder
storage temp.: −20°C
SMILES string: O.[Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@@H]1O
InChI: 1S/C15H24N2O17P2.2Na.H2O/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;;1H2/q;2*+1;/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;;/m1.../s1
InChI key: SRHFBUUOPANXBG-WSIJJEQHSA-L
biological source:
Saccharomyces cerevisiae
Quality Level:
300
Assay:
≥98%
form:
powder
storage temp.:
−20°C
SMILES string:
O.[Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@@H]1O
InChI:
1S/C15H24N2O17P2.2Na.H2O/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;;1H2/q;2*+1;/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;;/m1.../s1
InChI key:
SRHFBUUOPANXBG-WSIJJEQHSA-L
biological source: mouse
Quality Level: 200
Assay: __
form: buffered aqueous solution
storage temp.: __
SMILES string: __
InChI: __
InChI key: __
biological source:
mouse
Quality Level:
200
Assay:
__
form:
buffered aqueous solution
storage temp.:
__
SMILES string:
__
InChI:
__
InChI key:
__