5545561

Tocris Bioscience™ Hydroxy Dynasore

Dynamin inhibitor; analog of dynasore (Cat. No. 2897)

Manufacturer: Fischer Scientific

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Purity

>98%

Description

Hydroxy Dynasore

Product Type

Hydroxy Dynasore

Common Name

Dynamin Inhibitors

Molecular Weight (g/mol)

338.31

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Description

  • Dynamin inhibitor (IC50 values are 0.38 and 2.6 μM for dynamin 1 and 2 respectively)
  • Inhibits dynamin-mediated endocytosis in multiple cell types and reduces synaptic vesicle endocytosis in vitro
  • Prevents botulinum A internalization in hippocampal neurons
  • Also protects against botulinum A-induced muscle paralysis in rats
  • Analog of Dynasore (Cat
  • No
  • 2897).

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