5545563

Tocris Bioscience™ Ispinesib

High affinity and selective allosteric KSP inhibitor

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Description

Ispinesib

Molecular Weight (g/mol)

517.06

Product Type

Ispinesib

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Description

  • High affinity allosteric kinesin spindle protein (KSP) inhibitor (Ki app = 1.7 nM)
  • Exhibits >10,000-fold selectivity for KSP over a range of other mitotic kinesins
  • Inhibits proliferation and induces apoptosis of prostate and breast cancer cells in vitro
  • Induces tumor regression of breast cancer cell xenografts in mice.

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