PEP0105

Invitrogen™ Human IL-21 Synthetic Peptide

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 PEP0105-Each-of-1 In Stock ₹ 16,247.84

PEP0105 - Each of 1

₹ 16,247.84

In Stock

Quantity

1

Base Price: ₹ 16,247.84

GST (18%): ₹ 2,924.611

Total Price: ₹ 19,172.451

Gene ID (Entrez)

59067

Purification Method

purified

Common Name

Human IL-21

Content And Storage

-20°C

Format

Liquid

For Use With (Application)

Blocking Assay, Control

Lyophilized

No

Product Type

Peptide

Regulatory Status

RUO - research use only

Species

Human

Accession Number

Q9HBE4

Concentration

200 μg/mL

Description

Synthetic Peptide

Formulation

PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol

IL21

Preservative

0.02% sodium azide

Quantity

50 μg

Storage Buffer

PBS

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Description

  • IL-21 Synthetic Peptide, PEP-0105, from Invitrogen
  • IL-21 is a 17 kDa immunomodulatory cytokine produced mainly by Natural Killer Cells (NKT), T helper (Th) 17 and T follicular helper (TFH) cells
  • In TFH cells, IL-21 expression leads to autocrine signaling through the IL-21 receptor (IL-21R) and STAT3, which leads to additional transcriptional activation by Bcl6
  • As with IFN gamma for Th1 and IL-4 for Th2 cells, IL-21 is critical for TFH cell development and effector function
  • IL-21 plays a role in T cell-dependent B cell differentiation into plasma cells and memory cells, stimulation of IgG production and induction of apoptotic signaling in naive B cells
  • In Th17 cells, IL-21 expression and autocrine feedback through STAT3, IRF4 and ROR gamma t lead to upregulation of the IL-23R, thereby preparing Th17 cells for maturation and maintenance by the inflammatory cytokine IL-23
  • While upregulating IRF4 and ROR gamma t, IL-21 also mediates the downregulation of Foxp3
  • IL-21 deficient mice are protected from developing colitis upon chemical treatment by their inability to upregulate Th17-associated molecules
  • In comparison, elevated levels of IL-21 are present in chemically-induced colitis mouse models
  • This peptide corresponds to 15 amino acids near the center of human IL-21.PEP-0105 can be used as a blocking peptide with polyclonal antibody PA5-19981.

Compare Similar Items

Show Difference

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Invitrogen™

PEP0105

--


Gene ID (Entrez):
59067

Purification Method:
purified

Common Name:
Human IL-21

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
Q9HBE4

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
IL21

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Img

Invitrogen™

PEP0106

--


Gene ID (Entrez):
50615

Purification Method:
purified

Common Name:
Human IL21R

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
Q9HBE5

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
IL21R

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

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Invitrogen™

PEP0108

--


Gene ID (Entrez):
9466

Purification Method:
purified

Common Name:
Human TCCR

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
Q6UWB1

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
IL27RA

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Img

Invitrogen™

PEP0109

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Gene ID (Entrez):
9466

Purification Method:
purified

Common Name:
Human TCCR

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
Q6UWB1

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
IL27RA

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS