PEP0187

Invitrogen™ Human Bcl-2 Synthetic Peptide

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 PEP0187-Each-of-1 In Stock ₹ 16,247.84

PEP0187 - Each of 1

₹ 16,247.84

In Stock

Quantity

1

Base Price: ₹ 16,247.84

GST (18%): ₹ 2,924.611

Total Price: ₹ 19,172.451

Gene ID (Entrez)

596

Purification Method

purified

Common Name

Human Bcl-2

Content And Storage

-20°C

Format

Liquid

For Use With (Application)

Blocking Assay, Control

Lyophilized

No

Product Type

Peptide

Regulatory Status

RUO - research use only

Species

Human

Accession Number

P10415

Concentration

200 μg/mL

Description

Synthetic Peptide

Formulation

PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol

BCL2

Preservative

0.02% sodium azide

Quantity

50 μg

Storage Buffer

PBS

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Description

  • Bcl-2 Synthetic Peptide, PEP-0187, from Invitrogen
  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer
  • This peptide corresponds to 15 amino acids near the amino terminus of human Bcl-2.PEP-0187 can be used as a blocking peptide with polyclonal antibody PA5-20068.

Compare Similar Items

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Invitrogen™

PEP0187

--


Gene ID (Entrez):
596

Purification Method:
purified

Common Name:
Human Bcl-2

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
P10415

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
BCL2

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

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Invitrogen™

PEP0189

--


Gene ID (Entrez):
598

Purification Method:
purified

Common Name:
Human Bcl-xL

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
Q07817

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
BCL2L1

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

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Invitrogen™

PEP0195

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Gene ID (Entrez):
17082

Purification Method:
purified

Common Name:
Mouse ST2

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Mouse

Accession Number:
P14719

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
Il1rl1

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

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Invitrogen™

PEP0196

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Gene ID (Entrez):
24058

Purification Method:
purified

Common Name:
Mouse SIGIRR

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Mouse

Accession Number:
Q9JLZ8

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
Sigirr

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS