Human TRPM8, Synthetic Peptide, Invitrogen™

Description

• TRPM8 Synthetic Peptide, GST00017P, from Invitrogen
• TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius
• TRPM8 is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation
• TRPM8 is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium
• TRPM8 has an expression pattern within normal human tissues that is mostly restricted to prostate epithelial cells
• TRPM8 mRNA expression is at moderate levels in normal prostate tissue and appears to be elevated in prostate cancer
• Notably, TRPM8 mRNA was also expressed in a number of nonprostatic primary tumors of breast, colon, lung, and skin origin, whereas transcripts encoding TRPM8 were hardly detected or not detected in the corresponding normal human tissues
• GST00017P is the immunizing peptide for the antibody to TRPM8 (OSR00126W and OST00028W).GST00017P may be used as a control in various immunology applications.GST00017P maintain refrigerated at 2-8°C for up to 12 months
• After reconstitution keep at -20°C
• Avoid freeze and thaw cycles.Reconstitute with PBS or distilled water.