NanoFabTx™ NanoFlash PEG-PCL drug formulation screening kit

Description

• Application: NanoFabTx™ NanoFlash PEG-PCL drug formulation screening kit is a ready to use nanoformulation kit for flash nanoprecipitation synthesis of PEGylated poly(caprolactone) (PCL) nanoparticles for drug delivery research applications. This kit contains rationally selected PEGylated PCL polymers and stabilizer, enabling users to screen and select nanoformulations without the need for lenghty trial and error optimization. These PEGylated PCL polymers have been widely used in drug delivery systems for controlled drug release of many different types of therapeutic molecules.This kit has been curated and designed for flash nanoprecipitiaton (FNP) nanoparticle synthesis using a confined impingement jet (CIJ) mixer, such as the NanoFabTx™ NanoFlash CIJ Mixer, and detailed step-by-step instructions are provided.
• Features and Benefits: Ready-to-use nanoformulation kit for PEGylated nanoparticlesStep-by-step flash nanoprecipitation protocolCreate specifically sized, biodegradable, PEGylated PCL nanoparticlesMaximize the encapsulation of hydrophobic drugsThree different PEGylated PCL polymers are includedOptimized for 60 nm-150 nm nanoparticlesA flash nanoprecipitation protocol to prepare drug-encapsulated nanoparticles using the NanoFabTx™ NanoFlash CIJ Mixer is included and can be found under the Protocol section of this page.
• Legal Information: NANOFABTX is a trademark of Sigma-Aldrich Co. LLC