Description

• General description: Ring opening metathesis polymerization (ROMP) monomers are attractive building block for advanced polymeric materials in the biomedical field. 2,2-Bis(1-methylethyl)-1,3-dioxa-2-silacyclohept-5-ene , or the silyl ether based ROMP monomer iPrSi, is a bifunctional cyclic olefin that can be used to synthesize a variety of marcomolecules and polymers with diverse compositions and complex structures. iPrSi can copolymerize with a variety of norbornene derivatives including small molecules and macromolecules, enabling the formation of backbone-degradable copolymers that can be used in a variety of biomedical applications. The ROMP polymerization method is superior as it permits the tailorability of the resulting polymer material.
• Application: Synthesis of advanced polymeric materials for biomedical applications including: drug delivery molecular imaging self assembly hydrogels medical device coatings stimuli responsive material
• Features and Benefits: Copolymerize efficiency with a wide variety of norbornene-based (macro)monomers Controlled ROMP polymerization Silyl ether substitute can be tuned to control degradation