NanoFabTx™ for gene delivery

Description

• General description: Maleimide lipid mix for gene delivery and targeted delivery
• Application: With the NanoFabTx™ gene delivery maleimide lipid mix, researchers can simplify their drug development workflow. The ready to use mix enables the screening of different drug modalities such as oligonucleotides, nucleic acids (mRNA, DNA, siRNA), and vaccines without the need to develop new drug delivery formulations from scratch, ultimately speeding up the time it takes for innovative therapeutics to go from the bench to the clinic. The maleimide-functionalized surface of the LNP can be used to conjugate to many different thiol-containing biomolecules for active targeting. This ready-to-use lipid mix can also be used to screen different targeting moieties to determine what works best for your therapuetic and application. In addition, the lipid mix has been carefully crafted for enhanced gene delivery.
• Features and Benefits: A ready-to-use nanoformulation lipid blend to synthesize Maleimide-functionalized lipid nanoparticles Step-by-step protocols developed and tested by our formulation scientistsFlexible synthesis tool to create uniform and reproducible lipid nanoparticlesOptimized to make lipid nanoparticles around 100 nm with low polydispersityOptimized lipid blend for thiol-containing protein or antibody conjugationOptimized lipid blend for Maleimide-functionalized lipid nanoparticles for mRNA encapsulationFor more information, please refer to the protocol under the document section of this page.
• Legal Information: Legal Information NanoFabTx is a trademark of Sigma-Aldrich Co. LLC