Bicalutamide
British Pharmacopoeia (BP) Reference Standard
Manufacturer: Sigma Aldrich
CAS Number: 90357-06-5
Synonym(S): Bicalutamide (CDX), Casodex, Cosudex, N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | BP1115-100-MG | In Stock | ₹ 25,644.43 |
BP1115 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 25,644.43
GST (18%): ₹ 4,615.997
Total Price: ₹ 30,260.427
grade
pharmaceutical primary standard
API family
bicalutamide
form
solid
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
BP
application(s)
pharmaceuticalpharmaceutical small molecule
format
neat
storage temp.
2-8°C
SMILES string
CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F
InChI
1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
Other Options
Related Products
Description
- General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
- Application: Bicalutamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia. Also used in monographs such as:Bicalutamide Tablets
- Biochem/physiol Actions: Bicalutamide (CDX) is a non-steriodal Androgen Receptor (AR) antagonist and a pure antiandrogen. It acts via balancing histone acetylation/deacetylation and recruitment of coregulators. Bicalutamide (CDX) abolishes androgen-mediated expression. For example, MMP13 upregulation in prostate cancer, PLZF (promyelocytic leukemia zinc finger protein), and GADD45γ (growth arrest and DNA damage inducible, gamma). Bicalutamide (CDX) is inhibited by non-genomic, transcription-independent stimulation of PI3K/AKT phosphorylation by androgens.
- Packaging: Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
- Other Notes: Sales restrictions may apply.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 1 - Carc. 2 - Repr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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grade: pharmaceutical primary standard
API family: bicalutamide
form: solid
shelf life: limited shelf life, expiry date on the label
manufacturer/tradename: BP
application(s): pharmaceuticalpharmaceutical small molecule
format: neat
storage temp.: 2-8°C
SMILES string: CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F
InChI: 1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
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