S8626

Sulfadiazine

99.0-101.0%

Manufacturer: Sigma Aldrich

CAS Number: 68-35-9

Synonym(S): 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N1-(Pyrimidin-2-yl)sulfanilamide

Select a Size

Pack Size SKU Availability Price
25 G S8626-25-G In Stock ₹ 2,846.98
50 G S8626-50-G In Stock ₹ 3,842.88
100 G S8626-100-G In Stock ₹ 4,763.00
500 G S8626-500-G In Stock ₹ 18,305.08

S8626 - 25 G

₹ 2,846.98

In Stock

Quantity

1

Base Price: ₹ 2,846.98

GST (18%): ₹ 512.456

Total Price: ₹ 3,359.436

description

Solubility - Practically insoluble in water, slightly soluble in acetone, very slightly soluble in ethanol (96 per cent). It dissolves in solutions of alkali hydroxides and in dilute mineral acids.

Quality Level

200

Assay

99.0-101.0%

form

powder or crystals

color

white to faint yellow, faint pink

mp

253 °C (dec.) (lit.)

solubility

96% ethanol: very slightly solubleacetone: slightly solublewater: practically insoluble

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteriamycoplasma

Mode of action

DNA synthesis | interferesenzyme | inhibits

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2

Other Options

Image Product Name Manufacturer Price Range
11-101-5163
Sulfadiazine Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 10,866.12
11-101-5161
TraceCERT™ Sulfadiazine, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 20,106.60
11-101-5162
VETRANAL™ Sulfadiazine, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 6,502.56
NC1595584
eMolecules​ Sulfadiazine | 68-35-9 | MFCD00006065 | 5g
eMolecules​ ₹ 2,416.21
35033
Sulfadiazine
Supelco ₹ 5,401.68
PHR1343
Sulfadiazine
Supelco ₹ 10,695.10
1625009
Sulfadiazine
Sigma Aldrich ₹ 40,756.13
BP312
Sulfadiazine
Sigma Aldrich ₹ 24,767.60
Y0001480
Sulfadiazine for identification of impurity F
Sigma Aldrich ₹ 14,267.35
73901
Sulfadiazine
Supelco ₹ 17,850.43

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Description

  • General description: Chemical structure: sulfonamide
  • Application: Sulfadiazine is a short-acting sulfonamide that is commonly used with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome. It is also used to treat newborns with congenital infections[1]. Sulfadiazine has been used to control acute infections when studying murine models of reactivated toxoplasmosis[2].
  • Biochem/physiol Actions: Sulfadiazine is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfadiazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid[1]. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.Storage class (TRGS 510): Non Combustible Solids

SAFETY INFORMATION

Pictograms

GHS08,GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302,H361d,H411

Precautionary Statements

P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Solubility - Practically insoluble in water, slightly soluble in acetone, very slightly soluble in ethanol (96 per cent). It dissolves in solutions of alkali hydroxides and in dilute mineral acids.

Quality Level:
200

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powder or crystals

color:
white to faint yellow, faint pink

mp:
253 °C (dec.) (lit.)

solubility:
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antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriamycoplasma

Mode of action:
DNA synthesis | interferesenzyme | inhibits

SMILES string:
Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2

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