K1563

Thermo Scientific™ Tango™ CXCR6-blaU2OS Cells

Manufacturer: Thermo Scientific™

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Pack Size SKU Availability Price
Each of 1 K1563-Each-of-1 In Stock ₹ 9,05,224.80

K1563 - Each of 1

₹ 9,05,224.80

In Stock

Quantity

1

Base Price: ₹ 9,05,224.80

GST (18%): ₹ 1,62,940.464

Total Price: ₹ 10,68,165.264

Accession Number

NM_006564.1

Cell State

Dividing Cells

Cytoplasmic Tail

Native Tail

Gene Symbol

CXCR6

Product Line

Tango™

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

U2OS

Druggable Target

GPCR

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ CXCR6-bla U2OS cells• Tango™ CXCR6-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ CXCR6-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Population Status

Pool of Stable Cells

Quantity

2 x 106Cells

Target Entry

CXCR6

System Type

Tango™

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Description

  • The Tango™ CXCR6-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 6 (CXCR6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
  • The Tango™ CXCR6-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of CXCL16
  • These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.

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Img

Thermo Scientific™

K1563

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Accession Number:
NM_006564.1

Cell State:
Dividing Cells

Cytoplasmic Tail:
Native Tail

Gene Symbol:
CXCR6

Product Line:
Tango™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ CXCR6-bla U2OS cells• Tango™ CXCR6-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ CXCR6-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Pool of Stable Cells

Quantity:
2 x 106Cells

Target Entry:
CXCR6

System Type:
Tango™

Img

Thermo Scientific™

K1564

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Accession Number:
NM_000739.2

Cell State:
Dividing Cells

Cytoplasmic Tail:
Tail from GRPR GPCR

Gene Symbol:
M2

Product Line:
Tango™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ CHRM2-bla U2OS cells• Tango™ CHRM2-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ CHRM2-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Single Cell Clone Origin

Quantity:
2 x 106Cells

Target Entry:
CHRM2, M2

System Type:
Tango™

Img

Thermo Scientific™

K1567

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Accession Number:
NM_001841

Cell State:
Division-Arrested Cells

Cytoplasmic Tail:
Tail from AVPR2 GPCR

Gene Symbol:
CNR2

Product Line:
Tango™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ CNR2-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ CNR2-bla U2OS Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ CNR2-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Single Cell Clone Origin

Quantity:
1 Plate

Target Entry:
CNR2

System Type:
Tango™

Img

Thermo Scientific™

K1569

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Accession Number:
NM_016568

Cell State:
Dividing Cells

Cytoplasmic Tail:
Tail from GRPR GPCR

Gene Symbol:
RLN3R1

Product Line:
Tango™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ RLN3R1-bla U2OS cells• Tango™ RLN3R1-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ RLN3R1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Pool of Stable Cells

Quantity:
2 x 106Cells

Target Entry:
RLN3R1

System Type:
Tango™