K1715

Thermo Scientific™ GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1715-Each-of-1 In Stock ₹ 9,05,224.80

K1715 - Each of 1

₹ 9,05,224.80

In Stock

Quantity

1

Base Price: ₹ 9,05,224.80

GST (18%): ₹ 1,62,940.464

Total Price: ₹ 10,68,165.264

Accession Number

NM_000706.3

Cell State

Dividing Cells

Detection Method

Fluorescence

Gene Symbol

AVPR1a

Product Line

GeneBLAzer™

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

CHO-K1

Druggable Target

GPCR

Assay Entry

Cell-based beta lactamase reporter gene

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 cells• GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

For Use With (Application)

FRET

Population Status

Single Cell Clone Origin

Quantity

2 x 106cells

Target Entry

AVPR1A

System Type

GeneBLAzer™

Related Products

Img

Thermo Scientific™

K1735

--

Img

Thermo Scientific™

K1718

--

Img

Thermo Scientific™

K1716

--

Img

Thermo Scientific™

K1719

--

Img

Thermo Scientific™

K1561

--

Img

Thermo Scientific™

K1743

--

Img

Thermo Scientific™

K1723

--

Img

Thermo Scientific™

K1734

--

Description

  • GeneBLAzer™ AVPR1a-NFAT- bla CHO-K1 cells contain the human Arginine Vasopressin Receptor 1a (AVPR1a) stably integrated into the CellSensor™ NFAT- bla CHO-K1 cell line
  • CellSensor™ NFAT- bla CHO-K1 cells (Cat
  • No
  • K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element
  • The GeneBLAzer™ AVPR1a-NFAT- bla CHO-K1 cells are functionally validated for Z' and EC 50 concentrations of Vasopressin
  • In addition, GeneBLAzer™ AVPR1a-NFAT- bla CHO-K1 cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary
  • The family of receptors that recognize vasopressin and oxytocin consists of four members: vasopressin receptors 1a (AVPR1a), 1b (AVPR1b), and 2 (AVPR2), and the oxytocin (OT) receptor
  • AVPR1a, AVPR1b, and the OT receptor couple to the Gq/G11 class of G proteins and trigger the release of intracellular calcium when stimulated
  • AVPR2 receptors couple to Gs proteins and activate adenyl cyclase
  • All three AVPR receptors have high affinity for their endogenous ligand, vasopressin, but AVPR1b has less affinity for oxytocin than does AVPR1a or AVPR2
  • The hormones vasopressin and oxytocin are synthesized in the hypothalamus
  • Oxytocin causes contractions in the uterus during childbirth
  • The main functions of arginine vasopressin (AVP) are reabsorption of water by the kidneys and contraction of smooth muscle in arteries
  • This system may also play a role in memory and learning
  • For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

Compare Similar Items

Show Difference

Img

Thermo Scientific™

K1715

--


Accession Number:
NM_000706.3

Cell State:
Dividing Cells

Detection Method:
Fluorescence

Gene Symbol:
AVPR1a

Product Line:
GeneBLAzer™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
CHO-K1

Druggable Target:
GPCR

Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 cells• GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

For Use With (Application):
FRET

Population Status:
Single Cell Clone Origin

Quantity:
2 x 106cells

Target Entry:
AVPR1A

System Type:
GeneBLAzer™

Img

Thermo Scientific™

K1716

--


Accession Number:
NM_000740.2

Cell State:
Dividing Cells

Detection Method:
Fluorescence

Gene Symbol:
M3

Product Line:
GeneBLAzer™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
CHO-K1

Druggable Target:
GPCR

Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ M3-NFAT-blaCHO-K1 cells• GeneBLAzer™ M3-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ M3-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

For Use With (Application):
FRET

Population Status:
Single Cell Clone Origin

Quantity:
2 x 106Cells

Target Entry:
M3

System Type:
GeneBLAzer™

Img

Thermo Scientific™

K1717

--


Accession Number:
NM_004154.3

Cell State:
Dividing Cells

Detection Method:
Fluorescence

Gene Symbol:
P2RY6

Product Line:
GeneBLAzer™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
CHO-K1

Druggable Target:
GPCR

Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol/Includes:• GeneBLAzer™ P2RY6-NFAT-blaCHO-K1 cells• GeneBLAzer™ P2RY6-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ P2RY6-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

For Use With (Application):
FRET

Population Status:
Single Cell Clone Origin

Quantity:
2 x 106Cells

Target Entry:
P2RY6

System Type:
GeneBLAzer™

Img

Thermo Scientific™

K1718

--


Accession Number:
NM_000054

Cell State:
Dividing Cells

Detection Method:
Fluorescence

Gene Symbol:
AVPR2

Product Line:
GeneBLAzer™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
CHO-K1

Druggable Target:
GPCR

Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ AVPR2 CRE-blaCHO-K1 cells• GeneBLAzer™ AVPR2 CRE-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ AVPR2 CRE-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

For Use With (Application):
FRET

Population Status:
Single Cell Clone Origin

Quantity:
2 x 106Cells

Target Entry:
AVPR2

System Type:
GeneBLAzer™